The effect of Xuefu Zhuyu Decoction on in vitro endothelial progenitor cell tube formation.

The effect of Xuefu Zhuyu Decoction on in vitro endothelial progenitor cell tube formation.
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DOI:
10.1007/s11655-010-0050-y
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发表时间:
2010-02
影响因子:
2.9
通讯作者:
Chen Ke-ji
Chen Ke-ji
中科院分区:
医学3区
文献类型:
--
作者:
Gao Dong;Wu Li-ya;Jiao Yu-huan;Chen Wen-yuan;Chen Yan;Kaptchuk, Ted J.;Lu Bo;Song Jun;Chen Ke-ji

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To observe the in vitro effect of Xuefu Zhuyu Decoction on endothelial progenitor cell (EPC) tube formation. We prepared mononucleus cells from rat marrow by Ficoll density gradient centrifuge, separated EPCs by differential attachment method and observed, with inverted microscope, the effect of serum containing Xuefu Zhuyu Decoction (XFZYD) on endothelial progentor cell (EPC) tube formation. After 1 day, EPCs exposed to serum containing 5%, 10% and 15% XFZYD formed typical tube or vessel networks. Compared to the control group, the tube formation was 2 days ahead and most of the were smaller. XFZYD could induce EPCs angiogenesis and hasten tube formation, especially capillary vessel.
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