Progressive decline of cognition during the conversion from prodrome to psychosis with a characteristic pattern of the theory of mind compensated by neurocognition
Progressive decline of cognition during the conversion from prodrome to psychosis with a characteristic pattern of the theory of mind compensated by neurocognition
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从前驱症状转变为精神病期间，认知能力逐渐下降，具有由神经认知补偿的心理理论的特征模式
DOI：
10.1016/j.schres.2017.08.020
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发表时间：
2017-08
影响因子：
4.5
通讯作者：
Wang Jijun
中科院分区：
文献类型：
--
作者：
Zhang TianHong;Cui HuiRu;Wei YanYan;Tang YingYing;Xu LiHua;Tang XiaoChen;Zhu YiKang;Jiang LiJuan;Zhang Bin;Qian ZhenYing;Chow Annabelle;Liu XiaoHua;Li ChunBo;Xiao ZePing;Wang Jijun
在精神病进展过程中，神经认知和心理理论（ToM）能力之间的关联尚不清楚。这项研究包括83名患有轻微精神病综合征（APS）的个体，其中26名在18个月的随访期后转化为精神病（转化者）。在基线时进行综合认知测试（包括MATRICS共识认知成套测验、Faux-Pas任务和眼内阅读任务）。进行结构方程模型（SEM）分析，以估计神经认知对APS和健康对照（HC）数据集的ToM功能的影响。在基线时，转换者和非转换者组在认知表现的几个领域上存在显着差异。SEM分析表明，从神经认知到心理理论的路径在APS数据集中具有统计学显著性（p< 0.001）。然而，在HC数据集中，相同分析的结果不显著（p= 0.117）。神经认知与心理理论之间存在正相关，转换者组与非转换者组（p= 0.064）和HC组（p= 0.002）相比相关性最明显。心理理论能力和神经认知之间的相关性可能会在病情进展过程中增加，特别是对于那些在短期内转化为精神病的人。
The association between neurocognition and the theory of mind (ToM) abilities during the progression of psychosis is unclear. This study included 83 individuals with attenuated psychosis syndrome (APS), from which 26 converted to psychosis (converters) after a follow up period of 18 months. Comprehensive cognitive tests (including MATRICS Consensus Cognitive Battery, Faux-Pas Task, and Reading-Mind-in-Eyes Tasks) were administered at baseline. A structural equation modeling (SEM) analysis was conducted to estimate the effects of neurocognition on the ToM functioning in both APS and healthy controls (HC) datasets. At baseline, the converters and non-converters groups differed significantly on several domains of cognitive performance. The SEM analysis demonstrated that the path from neurocognition to ToM was statistically significant in the APS dataset (p< 0.001). However, in the HC dataset, the result of the same analysis was not significant (p= 0.117). Positive correlations between neurocognition and ToM were observed, and the most obvious correlations were found in the converters group compared with the non-converters group (p= 0.064) and compared with the HC group (p= 0.002). The correlation between ToM abilities and neurocognition may be increased during the progression of the condition, especially for individuals who convert to psychosis after a short period.
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影响因子：
2
作者：
Mourik K;Decrescenzo P;Brucato G;Gill KE;Arndt L;Kimhy D;Keilp JG;Girgis RR
通讯作者：
Girgis RR
影响因子：
25.8
作者：
Seidman LJ;Shapiro DI;Stone WS;Woodberry KA;Ronzio A;Cornblatt BA;Addington J;Bearden CE;Cadenhead KS;Cannon TD;Mathalon DH;McGlashan TH;Perkins DO;Tsuang MT;Walker EF;Woods SW
通讯作者：
Woods SW
DOI：
10.1016/j.ypsy.2012.07.042
发表时间：
2013
期刊：
Yearbook of Psychiatry and Applied Mental Health
影响因子：
--
作者：
P. Fusar-Poli;I. Bonoldi;Alison R. Yung;Stefan Borgwardt;M. Kempton;L. Valmaggia;Francesco Barale
通讯作者：
P. Fusar-Poli;I. Bonoldi;Alison R. Yung;Stefan Borgwardt;M. Kempton;L. Valmaggia;Francesco Barale
DOI：
10.1080/00332747.2015.1123592
发表时间：
2016-01
期刊：
Psychiatry
影响因子：
--
作者：
T. Zhang;Yingying Tang;Huiru Cui;Xi Lu;Lihua Xu;Xiaohua Liu;Huijun Li;Annabelle Chow;Yasong Du;Chunbo Li;K. Jiang;Ze-ping Xiao;Jijun Wang
通讯作者：
T. Zhang;Yingying Tang;Huiru Cui;Xi Lu;Lihua Xu;Xiaohua Liu;Huijun Li;Annabelle Chow;Yasong Du;Chunbo Li;K. Jiang;Ze-ping Xiao;Jijun Wang
影响因子：
6.6
作者：
Loewy, Rachel;Fisher, Melissa;Vinogradov, Sophia
通讯作者：
Vinogradov, Sophia