Nanosized diblock copolymer micelles as a scaffold for constructing a ratiometric fluorescent sensor for metal ion detection in aqueous media
Nanosized diblock copolymer micelles as a scaffold for constructing a ratiometric fluorescent sensor for metal ion detection in aqueous media
复制标题
纳米二嵌段共聚物胶束作为构建比率荧光传感器的支架，用于检测水介质中的金属离子
DOI：
10.1088/0957-4484/21/19/195501
复制
发表时间：
2010-05
期刊：
影响因子：
3.5
通讯作者：
Tong, Zhen
中科院分区：
文献类型：
--
作者：
Ma, Boling;Wu, Shuizhu;Zeng, Fang;Luo, Yulan;Zhao, Jianqing;Tong, Zhen
采用一种简单的策略，通过使用纳米级聚（环氧乙烷）-b-聚苯乙烯胶束作为支架，创建基于荧光共振能量转移（FRET）的比率传感系统，用于全水介质中的铁离子。疏水性荧光染料硝基苯并恶二唑基衍生物（NBD）作为能量转移供体，在胶束形成过程中被掺入胶束核心；选择螺内酰胺罗丹明衍生物 (SRhB-OH) 作为 Fe(III) 离子的敏感和选择性传感器，然后被“吸附”到胶束核心/电晕界面中。 Fe(III)诱导的SRhB-OH高效开环反应生成长波长罗丹明B荧光团，可作为能量受体；因此，胶束纳米颗粒可以作为基于 FRET 的铁离子比例检测系统。研究了PS嵌段长度对胶束离子传感性能的影响，发现由中等嵌段长度的共聚物(PEO113-b-PS115)形成的胶束更适合作为FRET系统的支架，并且对Fe(III)表现出灵敏和选择性的传感能力，检测限为1 µM。这种基于纳米粒子的传感策略可用于通过用其他合适的染料替换当前的染料来构建其他比率化学传感器。
A facile strategy was employed to create a fluorescence resonance energy transfer (FRET) based ratiometric sensing system for ferric ions in all-aqueous media by using nanosized poly(ethylene oxide)-b-polystyrene micelles as the scaffold. A hydrophobic fluorescent dye nitrobenzoxadiazolyl derivative (NBD), which served as the energy transfer donor, was incorporated into the micelle core during the micelle formation; a spirolactam rhodamine derivative (SRhB-OH) was chosen as a sensitive and selective sensor for Fe(III) ions and was then ‘adsorbed’ into the micelle core/corona interface. A highly efficient ring-opening reaction of SRhB-OH induced by Fe(III) generates the long-wavelength rhodamine B fluorophore which can act as the energy acceptor; thus, the micelle nanoparticles can serve as a FRET-based ratiometric detection system for ferric ions. The effects of PS block length on the ion sensing performance of the micelles were investigated, and it has been found that the micelles formed by the copolymer with moderate block length (PEO113-b-PS115) were preferable as the scaffold for the FRET system and exhibited a sensitive and selective sensing capacity for Fe(III) with a detection limit of 1 µM. This nanoparticle-based sensing strategy may be utilized to construct other ratiometric chemosensors by replacing the current dyes with other suitable ones.
登录
查看更多内容
DOI：
10.1021/la9033244
发表时间：
2010-03
期刊：
Langmuir : the ACS journal of surfaces and colloids
影响因子：
--
作者：
Meiyun Xu;Shuizhu Wu;Fang Zeng;Changmin Yu
通讯作者：
Meiyun Xu;Shuizhu Wu;Fang Zeng;Changmin Yu
影响因子：
2.9
作者：
Cicchetti, G;Biernacki, M;Allen, PG
通讯作者：
Allen, PG
影响因子：
3.5
作者：
P. Wingert;Hiroshi Mizukami;Agnes Ostafin
通讯作者：
P. Wingert;Hiroshi Mizukami;Agnes Ostafin
影响因子：
3.5
作者：
E. Le Moal;S. Lévêque-Fort;M. Potier;E. Fort
通讯作者：
E. Le Moal;S. Lévêque-Fort;M. Potier;E. Fort
影响因子：
5.5
作者：
Cai, YL;Armes, SP
通讯作者：
Armes, SP