Dairy foods and dairy proteins in the management of type 2 diabetes: a systematic review of the clinical evidence.
Dairy foods and dairy proteins in the management of type 2 diabetes: a systematic review of the clinical evidence.
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DOI：
10.3945/an.114.007690
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发表时间：
2015-05
期刊：
影响因子：
--
通讯作者：
Comerford KB
中科院分区：
文献类型：
--
作者：
Pasin G;Comerford KB
2型糖尿病（T2DM）是一个日益严重的公共卫生问题，影响全球数亿人，每年给全球经济造成数千亿美元的损失。这种慢性疾病会损害血管，并增加其他心脏代谢疾病的风险，如心血管疾病和中风。如果不加以管理，它也可能导致神经损伤，肾损伤，失明和截肢。在大多数情况下，这些症状可以通过简单的饮食调整和适当的营养来预防或减少。因此，确定用于预防和管理T2 DM的相对便宜且易于实施的饮食改变对地球仪周围的人类健康和医疗保健模式具有相当大的价值。流行病学研究一致表明，富含蛋白质的乳制品有利于降低发生T2DM的风险。关于乳制品和乳制品蛋白质的临床证据（即，酪蛋白和乳清蛋白）已经显示出改善T2DM个体的胰岛素分泌的前景。然而，在T2DM受试者中补充乳制品蛋白的临床研究仅限于急性研究。这些研究大多是描述性的，并没有关注重要的T2DM终点，如预防、管理或治疗。显然需要进行长期研究，以帮助研究人员和医疗专业人员更好地了解持续摄入乳制品蛋白质对T2DM患者代谢健康的影响。
Type 2 diabetes mellitus (T2DM) is a growing public health concern affecting hundreds of millions of people worldwide and costing the global economy hundreds of billions of dollars annually. This chronic disease damages the blood vessels and increases the risk of other cardiometabolic ailments such as cardiovascular disease and stroke. If left unmanaged it can also lead to nerve damage, kidney damage, blindness, and amputation. For the most part, many of these symptoms can be prevented or reduced through simple dietary modifications and proper nutrition. Therefore, identifying relatively inexpensive and easily implementable dietary modifications for the prevention and management of T2DM is of considerable value to human health and healthcare modalities around the globe. Protein-rich dairy products have consistently been shown in epidemiologic studies to be beneficial for reducing the risk of developing T2DM. The clinical evidence regarding both dairy foods and dairy proteins (i.e., casein and whey protein) have shown promise for improving insulin secretion in individuals with T2DM. However, the clinical research on dairy protein supplementation in subjects with T2DM has been limited to acute studies. These studies have been mostly descriptive and have not been focused on important T2DM endpoints such as prevention, management, or treatment. Long-term studies are clearly needed to help researchers and medical professionals better understand the effects of consistent dairy protein intake on the metabolic health of humans with T2DM.
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DOI：
10.1097/mco.0b013e32834b89da
发表时间：
2011-11-01
影响因子：
3.1
作者：
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通讯作者：
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影响因子：
105.7
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影响因子：
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作者：
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影响因子：
8
作者：
Jonker, J. T.;Wijngaarden, M. A.;Smit, J. W. A.
通讯作者：
Smit, J. W. A.
影响因子：
5.5
作者：
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