Prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) definition: findings from the Hertfordshire Cohort Study (HCS).
Prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) definition: findings from the Hertfordshire Cohort Study (HCS).
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DOI：
10.1093/ageing/afs197
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发表时间：
2013-05
期刊：
影响因子：
6.7
通讯作者：
Aihie Sayer A
中科院分区：
文献类型：
--
作者：
Patel HP;Syddall HE;Jameson K;Robinson S;Denison H;Roberts HC;Edwards M;Dennison E;Cooper C;Aihie Sayer A
简介：肌肉减少症与不良的健康结果有关。本研究的目的是使用欧洲老年人肌肉减少症工作组（EWGSOP）共识定义描述英国社区居住老年人肌肉减少症的患病率。研究方法：我们将EWGSOP定义应用于103名参与赫特福德郡肌肉减少症研究（HSS）的社区居民男性，使用双能X线吸收测定法（DXA）的最低三分之一瘦体重（LM）和基于皮褶的无脂肪体重（FFM）的最低三分之一作为低肌肉质量的标志。我们还在赫特福德郡队列研究（HCS）的765名男性和1，022名女性参与者中使用了FFM方法。在有和没有肌肉减少症的参与者中比较了身体尺寸，身体表现和自我报告的健康状况。结果：当使用DXA LM和FFM的最低三分之一时，HSS男性（平均年龄73岁）的肌肉减少症患病率分别为6.8%和7.8%。DXA LM与FFM高度相关（0.91，P < 0.001）。HCS男性和女性（平均年龄67岁）的肌肉减少症患病率分别为4.6%和7.9%。患有肌肉减少症的HSS和HCS参与者更矮，体重更轻，身体表现更差。患有肌肉减少症的HCS男性和女性自我报告的一般健康状况和身体功能评分较差。结论：这是描述英国社区居住老年人肌肉减少症患病率的首批研究之一。EWGSOP共识定义对于肌少症病例发现具有实际用途。下一步是将这一共识定义用于其他老龄化群体和各种保健环境中的老年人。
Introduction: sarcopenia is associated with adverse health outcomes. The aim of this study was to describe the prevalence of sarcopenia in community-dwelling older people in the UK using the European Working Group on Sarcopenia in Older People (EWGSOP) consensus definition. Methods: we applied the EWGSOP definition to 103 community-dwelling men participating in the Hertfordshire Sarcopenia Study (HSS) using both the lowest third of dual-energy X-ray absorptiometry (DXA) lean mass (LM) and the lowest third of skin-fold-based fat-free mass (FFM) as markers of low muscle mass. We also used the FFM approach among 765 male and 1,022 female participants in the Hertfordshire Cohort Study (HCS). Body size, physical performance and self-reported health were compared in participants with and without sarcopenia. Results: the prevalence of sarcopenia in HSS men (mean age 73 years) was 6.8% and 7.8% when using the lowest third of DXA LM and FFM, respectively. DXA LM and FFM were highly correlated (0.91, P < 0.001). The prevalence of sarcopenia among the HCS men and women (mean age 67 years) was 4.6% and 7.9%, respectively. HSS and HCS participants with sarcopenia were shorter, weighed less and had worse physical performance. HCS men and women with sarcopenia had poorer self-reported general health and physical functioning scores. Conclusions: this is one of the first studies to describe the prevalence of sarcopenia in UK community-dwelling older people. The EWGSOP consensus definition was of practical use for sarcopenia case finding. The next step is to use this consensus definition in other ageing cohorts and among older people in a range of health-care settings.
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影响因子：
120.7
作者：
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通讯作者：
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