The role of solar and geomagnetic activity in endothelial activation and inflammation in the NAS cohort.
The role of solar and geomagnetic activity in endothelial activation and inflammation in the NAS cohort.
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DOI:
10.1371/journal.pone.0268700
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发表时间:
2022
期刊:
影响因子:
3.7
通讯作者:
中科院分区:
文献类型:
--
作者:
This study investigated the associations between solar and geomagnetic activity and circulating biomarkers of systemic inflammation and endothelial activation in the Normative Aging Study (NAS) cohort. Mixed effects models with moving day averages from day 0 to day 28 were used to study the associations between solar activity (sunspot number (SSN), interplanetary magnetic field (IMF)), geomagnetic activity (planetary K index (Kp index), and various inflammatory and endothelial markers. Biomarkers included intracellular adhesion molecule-1 (sICAM-1), vascular cell adhesion molecule-1 (sVCAM-1), C-reactive protein (CRP), and fibrinogen. After adjusting for demographic and meteorological variables, we observed significant positive associations between sICAM-1 and sVCAM-1 concentrations and solar and geomagnetic activity parameters: IMF, SSN, and Kp. Additionally, a negative association was observed between fibrinogen and Kp index and a positive association was observed for CRP and SSN. These results demonstrate that solar and geomagnetic activity might be upregulating endothelial activation and inflammation.
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DOI:
10.1097/ede.0b013e31824523f0
发表时间:
2012-03
期刊:
Epidemiology (Cambridge, Mass.)
影响因子:
--
作者:
Bind MA;Baccarelli A;Zanobetti A;Tarantini L;Suh H;Vokonas P;Schwartz J
通讯作者:
Schwartz J
影响因子:
10.4
作者:
Alexeeff SE;Coull BA;Gryparis A;Suh H;Sparrow D;Vokonas PS;Schwartz J
通讯作者:
Schwartz J
影响因子:
20.9
作者:
Hathaway DH
通讯作者:
Hathaway DH
影响因子:
2.5
作者:
Burch, JB;Reif, JS;Yost, MG
通讯作者:
Yost, MG
影响因子:
10.4
作者:
Dai L;Zanobetti A;Koutrakis P;Schwartz JD
通讯作者:
Schwartz JD