Associations of fine particulate matter species with mortality in the United States: a multicity time-series analysis.
Associations of fine particulate matter species with mortality in the United States: a multicity time-series analysis.
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DOI：
10.1289/ehp.1307568
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发表时间：
2014-08
影响因子：
10.4
通讯作者：
Schwartz JD
中科院分区：
文献类型：
--
作者：
Dai L;Zanobetti A;Koutrakis P;Schwartz JD
背景：流行病学研究已经研究了PM2.5与死亡率之间的关系，但PM2.5相关影响的季节性变化以及物种的相对重要性仍然不确定。目的：我们估计了PM2.5种类对死亡率的影响，以及入渗率如何改变这种关联。方法：使用城市季节特异性泊松回归，我们估计了PM2.5对2000-2006年美国75个城市中各种原因、心血管疾病（CVD）、心肌梗死（MI）、中风和呼吸系统疾病造成的约450万例死亡的影响。我们增加了PM2.5与单个物种的月平均物种-PM2.5比例之间的相互作用项，以确定每个物种的相对毒性。我们使用多元元回归将各城市的结果结合起来，并控制渗透。结果：我们估计，2天平均PM2.5浓度每增加10 μg/m3，全因死亡率增加1.18% (95% CI: 0.93, 1.44%)，心血管疾病增加1.03% (95% CI: 0.65, 1.41%)，心肌梗死增加1.22% (95% CI: 0.62, 1.82%)，中风增加1.76% (95% CI: 1.01, 2.52%)，呼吸系统死亡增加1.71% （95% CI: 1.06, 2.35%）。这些社团在春天是最大的。硅、钙和硫与更多的全因死亡率相关，而硫与更多的呼吸性死亡相关。县级吸烟和饮酒与PM2.5的估计影响较大有关。结论：我们的研究表明，PM2.5与死亡风险增加有关，随季节和物种而变化。研究结果表明，仅凭质量可能不足以评估颗粒物对健康的影响。引用本文：Dai L， Zanobetti A, Koutrakis P, Schwartz JD。2014. 美国细颗粒物种类与死亡率的关联：多城市时间序列分析。环境健康展望122:837-842；http://dx.doi.org/10.1289/ehp.1307568
Background: Epidemiological studies have examined the association between PM2.5 and mortality, but uncertainty remains about the seasonal variations in PM2.5-related effects and the relative importance of species. Objectives: We estimated the effects of PM2.5 species on mortality and how infiltration rates may modify the association. Methods: Using city–season specific Poisson regression, we estimated PM2.5 effects on approximately 4.5 million deaths for all causes, cardiovascular disease (CVD), myocardial infarction (MI), stroke, and respiratory diseases in 75 U.S. cities for 2000–2006. We added interaction terms between PM2.5 and monthly average species-to-PM2.5 proportions of individual species to determine the relative toxicity of each species. We combined results across cities using multivariate meta-regression, and controlled for infiltration. Results: We estimated a 1.18% (95% CI: 0.93, 1.44%) increase in all-cause mortality, a 1.03% (95% CI: 0.65, 1.41%) increase in CVD, a 1.22% (95% CI: 0.62, 1.82%) increase in MI, a 1.76% (95% CI: 1.01, 2.52%) increase in stroke, and a 1.71% (95% CI: 1.06, 2.35%) increase in respiratory deaths in association with a 10-μg/m3 increase in 2-day averaged PM2.5 concentration. The associations were largest in the spring. Silicon, calcium, and sulfur were associated with more all-cause mortality, whereas sulfur was related to more respiratory deaths. County-level smoking and alcohol were associated with larger estimated PM2.5 effects. Conclusions: Our study showed an increased risk of mortality associated with PM2.5, which varied with seasons and species. The results suggest that mass alone might not be sufficient to evaluate the health effects of particles. Citation: Dai L, Zanobetti A, Koutrakis P, Schwartz JD. 2014. Associations of fine particulate matter species with mortality in the United States: a multicity time-series analysis. Environ Health Perspect 122:837–842; http://dx.doi.org/10.1289/ehp.1307568
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影响因子：
10.4
作者：
Krall JR;Anderson GB;Dominici F;Bell ML;Peng RD
通讯作者：
Peng RD
DOI：
10.1164/rccm.200611-1627oc
发表时间：
2007-08-15
影响因子：
24.7
作者：
Chuang, Kai-Jen;Chan, Chang-Chuan;Tang, Chin-Sheng
通讯作者：
Tang, Chin-Sheng
DOI：
10.1097/ede.0b013e3181812bb7
发表时间：
2008-09
期刊：
Epidemiology (Cambridge, Mass.)
影响因子：
--
作者：
Franklin M;Koutrakis P;Schwartz P
通讯作者：
Schwartz P
影响因子：
10.4
作者：
Baja ES;Schwartz JD;Wellenius GA;Coull BA;Zanobetti A;Vokonas PS;Suh HH
通讯作者：
Suh HH
美国健康效应研究中PM（2.5）化学成分的空间和时间变化。
影响因子：
10.4
作者：
Bell ML;Dominici F;Ebisu K;Zeger SL;Samet JM
通讯作者：
Samet JM