Immunity, host physiology, and behaviour in infected vectors.

Immunity, host physiology, and behaviour in infected vectors.
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DOI:
10.1016/j.cois.2017.03.001
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发表时间:
2017-04
影响因子:
5.3
通讯作者:
Cator LJ
Cator LJ
中科院分区:
农林科学2区
文献类型:
--
作者:
Murdock CC;Luckhart S;Cator LJ

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当感染改变宿主的行为,使病原体受益时,这种行为被称为操纵。在许多不同的系统中,有几个这种引人入胜的现象的例子。病媒传播的疾病也不例外。在某些情况下,正如术语所暗示的那样,病原体直接干扰宿主进程以控制行为。然而,寄主对感染的反应和寄主生理可能在这些表型中发挥重要作用。我们强调了从最近在感染疟疾寄生虫的蚊子中改变寄主寻找的工作中考虑宿主反应和生理学的重要性,并认为这种一般方法将在媒介传播的疾病系统中提供有用的见解。
When infection alters host behaviour such that the pathogen benefits, the behaviour is termed a manipulation. There are several examples of this fascinating phenomenon in many different systems. Vector-borne diseases are no exception. In some instances, as the term implies, pathogens directly interfere with host processes to control behaviour. However, host response to infection and host physiology are likely to play important roles in these phenotypes. We highlight the importance of considering host response and physiology from recent work on altered host-seeking in malaria parasite-infected mosquitoes and argue that this general approach will provide useful insights across vector-borne disease systems.
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