CyanoBase: a large-scale update on its 20th anniversary.

CyanoBase: a large-scale update on its 20th anniversary.
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DOI:
10.1093/nar/gkw1131
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发表时间:
2017-01-04
影响因子:
14.9
通讯作者:
Nakamura Y
Nakamura Y
中科院分区:
生物学2区
文献类型:
--
作者:
Fujisawa T;Narikawa R;Maeda SI;Watanabe S;Kanesaki Y;Kobayashi K;Nomata J;Hanaoka M;Watanabe M;Ehira S;Suzuki E;Awai K;Nakamura Y

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二十年前确定了第一个蓝藻基因组序列,同时开发了第一个蓝藻数据库http://genome.microbedb.jp/cyanobase),,以便更有效地利用这些基因组信息。从那时起,CyanoBase一直在不断扩展,并收到了几次更新。在这里,我们描述了数据库的一次新的大规模更新,恰逢它成立20周年。我们扩大了蓝藻基因组序列的数量,从39种增加到376种,包括86个完整基因组和290个草稿基因组。我们还优化了大型基因组数据的用户界面,包括语义网技术和JBROWSE的使用,并通过对集胞藻的重新注释扩展了基于社区的重新注释资源。由蓝藻研究界提出的PCC 6803。这些更新显著改进了蓝藻碱基,为蓝藻研究提供了蓝藻基因组注释作为参考。
The first ever cyanobacterial genome sequence was determined two decades ago and CyanoBase (http://genome.microbedb.jp/cyanobase), the first database for cyanobacteria was simultaneously developed to allow this genomic information to be used more efficiently. Since then, CyanoBase has constantly been extended and has received several updates. Here, we describe a new large-scale update of the database, which coincides with its 20th anniversary. We have expanded the number of cyanobacterial genomic sequences from 39 to 376 species, which consists of 86 complete and 290 draft genomes. We have also optimized the user interface for large genomic data to include the use of semantic web technologies and JBrowse and have extended community-based reannotation resources through the re-annotation of Synechocystis sp. PCC 6803 by the cyanobacterial research community. These updates have markedly improved CyanoBase, providing cyanobacterial genome annotations as references for cyanobacterial research.
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