Mediterranean diet and cognitive health: Initial results from the Hellenic Longitudinal Investigation of Ageing and Diet.
Mediterranean diet and cognitive health: Initial results from the Hellenic Longitudinal Investigation of Ageing and Diet.
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DOI：
10.1371/journal.pone.0182048
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发表时间：
2017
期刊：
影响因子：
3.7
通讯作者：
Scarmeas N
中科院分区：
文献类型：
--
作者：
Anastasiou CA;Yannakoulia M;Kosmidis MH;Dardiotis E;Hadjigeorgiou GM;Sakka P;Arampatzi X;Bougea A;Labropoulos I;Scarmeas N
地中海饮食模式与许多退行性疾病的风险降低有关，特别是认知功能;然而，来自地中海地区的相关信息非常有限，地中海饮食的原型通常是坚持的。此外，使用先验截止值的预定义地中海饮食（MeDi）评分很少使用，限制了不同人群之间的比较，从而限制了相关性的外部有效性。最后，MeDi的各个组成部分之间的关联（即，食物组、大量营养素）和认知表现的特定方面很少被探索。我们在希腊的一个代表性人群队列中评估了遵守先验定义的地中海饮食模式及其组成部分与痴呆和认知功能特定方面的关联。来自希腊老龄化和饮食纵向调查（HELIAD）的参与者，这是一项正在进行的基于人群的研究，在希腊地区的代表性样本中探索饮食与认知表现之间的潜在关联，被纳入本分析。痴呆症的诊断是由一个完整的临床和神经心理学评估，而认知性能进行了评估，根据五个认知领域（记忆，语言，注意力速度，执行功能，视觉空间感知）和综合认知评分。根据一份详细的食物频率问卷，通过先验评分（范围0-55）评估对Medi的依从性。在1，865名受试者（平均年龄73±6岁，41%为男性）中，90名被诊断患有痴呆症，223名患有轻度认知障碍。地中海饮食评分（MedDietScore）每增加一个单位，患痴呆症的几率就会降低10%。坚持Medi也与记忆，语言，视觉空间感知和综合认知评分的更好表现相关;记忆的相关性最强。鱼类消费与痴呆症呈负相关，认知能力与非精制谷物消费呈正相关。我们的研究结果表明，坚持Medi与希腊老年人更好的认知能力和更低的痴呆率有关。因此，Medi在其先验构建的原型形式可能在传统的地中海人口的认知效益。
The Mediterranean dietary pattern has been associated with a decreased risk of many degenerative diseases and cognitive function in particular; however, relevant information from Mediterranean regions, where the prototype Mediterranean diet is typically adhered to, have been very limited. Additionally, predefined Mediterranean diet (MeDi) scores with use of a priori cut-offs have been used very rarely, limiting comparisons between different populations and thus external validity of the associations. Finally, associations between individual components of MeDi (i.e., food groups, macronutrients) and particular aspects of cognitive performance have rarely been explored. We evaluated the association of adherence to an a priori defined Mediterranean dietary pattern and its components with dementia and specific aspects of cognitive function in a representative population cohort in Greece. Participants from the Hellenic Longitudinal Investigation of Ageing and Diet (HELIAD), an on-going population-based study, exploring potential associations between diet and cognitive performance in a representative sample from Greek regions, were included in this analysis. Diagnosis of dementia was made by a full clinical and neuropsychological evaluation, while cognitive performance was assessed according to five cognitive domains (memory, language, attention-speed, executive functioning, visuospatial perception) and a composite cognitive score. Adherence to MeDi was evaluated by an a priori score (range 0–55), derived from a detailed food frequency questionnaire. Among 1,865 individuals (mean age 73±6 years, 41% male), 90 were diagnosed with dementia and 223 with mild cognitive impairment. Each unit increase in the Mediterranean dietary score (MedDietScore) was associated with a 10% decrease in the odds for dementia. Adherence to the MeDi was also associated with better performance in memory, language, visuospatial perception and the composite cognitive score; the associations were strongest for memory. Fish consumption was negatively associated with dementia and cognitive performance positively associated with non-refined cereal consumption. Our results suggest that adherence to the MeDi is associated with better cognitive performance and lower dementia rates in Greek elders. Thus, the MeDi in its a priori constructed prototype form may have cognitive benefits in traditional Mediterranean populations.
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影响因子：
9.9
作者：
Cummings, JL
通讯作者：
Cummings, JL
DOI：
10.1016/j.numecd.2010.10.015
发表时间：
2012-08-01
影响因子：
3.9
作者：
Bountziouka, V.;Bathrellou, E.;Panagiotakos, D. B.
通讯作者：
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作者：
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通讯作者：
STERN, Y
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作者：
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通讯作者：
Vaupel, James W.
影响因子：
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作者：
Gardener, Hannah;Scarmeas, Nikolaos;Wright, Clinton B.
通讯作者：
Wright, Clinton B.