3D superimposition and understanding temporomandibular joint arthritis.

3D superimposition and understanding temporomandibular joint arthritis.
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DOI:
10.1111/ocr.12070
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发表时间:
2015-04
影响因子:
3.1
通讯作者:
Paniagua B
Paniagua B
中科院分区:
医学3区
文献类型:
--
作者:
Cevidanes LH;Gomes LR;Jung BT;Gomes MR;Ruellas AC;Goncalves JR;Schilling J;Styner M;Nguyen T;Kapila S;Paniagua B

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采用新颖的成像统计建模方法研究169个颞下颌关节(TMJ)髁的三维形态学变化。密歇根大学口腔正畸和儿科牙科学系。本研究收集了69例长期TMJ骨关节炎(OA,平均年龄39.1±15.7岁)、15例初诊诊断为OA的患者(平均年龄44.9±14.8岁)和7例健康对照(平均年龄43±12.4岁)的锥形束CT扫描。建立髁突的三维表面模型,并在每个模型上建立相应的点。统计框架包括方向-投影-排列(DiProPerm),用于检验临床和影像学诊断确定的健康对照组与OA组之间差异的统计学意义。骨性关节炎和健康受试者的髁突形态差异很大,分类从轻度到重度骨变性或过度生长。DiProPerm统计支持健康对照组与OA初始诊断组之间(t=6.6,经验p值= 0.006)、健康组与OA长期诊断组之间(t= 7.2,经验p值= 0)的显著差异。与健康对照相比,OA受试者除前表面外,所有尺寸的平均髁突都明显较小,即使在最初诊断为OA的受试者中也是如此。这种新的统计模型的髁突形态允许更有针对性的分类这种情况的发展比以前可能的。
To investigate the 3D morphological variations in 169 Temporomandibular Joint (TMJ) condyles, using novel imaging statistical modeling approaches. The Department of Orthodontics and Pediatric Dentistry at the University of Michigan. Cone beam CT scans were acquired from 69 subjects with long-term TMJ osteoarthritis (OA, mean age 39.1 ± 15.7 years), 15 subjects at initial consult diagnosis of OA (mean age 44.9 ± 14.8 years) and 7 healthy controls (mean age 43 ± 12.4 years). 3D surface models of the condyles were constructed and homologous correspondent points on each model were established. The statistical framework included Direction-Projection-Permutation (DiProPerm) for testing statistical significance of the differences between healthy controls and the OA groups determined by clinical and radiographic diagnoses. Condylar morphology in OA and healthy subjects varied widely with categorization from mild to severe bone degeneration or overgrowth. DiProPerm statistics supported a significant difference between the healthy control group and the initial diagnosis of OA group (t=6.6, empirical p-value = 0.006), and between healthy and long term-diagnosis of OA group (t = 7.2, empirical p-value = 0). Compared with healthy controls, the average condyle in OA subjects was significantly smaller in all dimensions, except its anterior surface, even in subjects with initial diagnosis of OA. This new statistical modeling of condylar morphology allows the development of more targeted classifications of this condition than previously possible.
DOI: 10.1016/j.tripleo.2010.01.008
发表时间: 2010-07
期刊: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
影响因子: --
作者:
Cevidanes LH;Hajati AK;Paniagua B;Lim PF;Walker DG;Palconet G;Nackley AG;Styner M;Ludlow JB;Zhu H;Phillips C
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DOI: 10.1007/s00256-010-0943-z
发表时间: 2011-01
期刊: SKELETAL RADIOLOGY
影响因子: 2.1
作者:
Schneider, Erika;Lo, Grace H.;Sloane, Gretchen;Fanella, Lynn;Hunter, David J.;Eaton, Charles B.;McAlindon, Timothy E.
通讯作者: McAlindon, Timothy E.
DOI: 10.1016/j.tripleo.2009.02.023
发表时间: 2009-06-01
期刊: ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY
影响因子: --
作者:
Ahmad, Mansur;Hollender, Lars;Schiffman, Eric L.
通讯作者: Schiffman, Eric L.
DOI: 10.1186/ar2655
发表时间: 2009
影响因子: 4.9
作者:
Abramson SB;Attur M
通讯作者: Attur M