Advances in passively driven microfluidics and lab-on-chip devices: a comprehensive literature review and patent analysis.

Advances in passively driven microfluidics and lab-on-chip devices: a comprehensive literature review and patent analysis.
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DOI:
10.1039/d0ra00263a
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发表时间:
2020-03-19
期刊:
影响因子:
3.9
通讯作者:
--
中科院分区:
化学3区
文献类型:
--
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多年来,被动驱动芯片微流控实验室的发展一直在不断增加。在被动方法中,微流体通常在没有任何外部致动器、场或电源的情况下被驱动和操作。被动微流控技术采用渗透、毛细管作用、表面张力、压力、重力驱动流、静水流和真空来实现流体流动。非常需要探索快速、紧凑、便携且易于使用的芯片实验室。这些技术的发展对于满足当前的需求至关重要。研究人员强调了该领域的巨大潜力,需要探索开发快速无源芯片实验室以满足市场/研究人员的需求。本文进行了全面的综述以及专利分析,列出了被动微流控技术的最新进展以及相关机制和应用。被动驱动微流体和 LOC 装置采用不同的方法。
The development of passively driven microfluidic labs on chips has been increasing over the years. In the passive approach, the microfluids are usually driven and operated without any external actuators, fields, or power sources. Passive microfluidic techniques adopt osmosis, capillary action, surface tension, pressure, gravity-driven flow, hydrostatic flow, and vacuums to achieve fluid flow. There is a great need to explore labs on chips that are rapid, compact, portable, and easy to use. The evolution of these techniques is essential to meet current needs. Researchers have highlighted the vast potential in the field that needs to be explored to develop rapid passive labs on chips to suit market/researcher demands. A comprehensive review, along with patent analysis, is presented here, listing the latest advances in passive microfluidic techniques, along with the related mechanisms and applications. Different approaches employed in the passively driven microfluidics and LOC devices.
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