Latex micro-balloon pumping in centrifugal microfluidic platforms.
Latex micro-balloon pumping in centrifugal microfluidic platforms.
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DOI：
10.1039/c3lc51116b
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发表时间：
2014-03-07
期刊：
影响因子：
6.1
通讯作者：
Madou M
中科院分区：
文献类型：
--
作者：
Aeinehvand MM;Ibrahim F;Harun SW;Al-Faqheri W;Thio TH;Kazemzadeh A;Madou M
离心微流体平台已经成为即时诊断工具。然而，离心力的单向性质限制了单个微流体盘上的多步过程的可用空间。为了克服这种限制，先前已经提出了在高旋转速度下致动的被动气动泵送方法，以克服离心力泵送液体。本文介绍了一种新型的微球抽吸方法，该方法依赖于储存在乳胶膜中的弹性能量。它在低转速下工作，并向圆盘中心泵送更大体积的液体。已经开发了两种不同的微球泵送设计，以研究在0至1500 rpm的旋转频率范围内的泵性能和容量。对微球泵在离心式微流控平台上的行为进行了理论分析，并与实验数据进行了比较。实验数据表明，与以前开发的气动泵送方法相比，所开发的泵送方法显著降低了泵送液体所需的转速。在一定转速范围内，通过调节微球的尺寸，可以实现所需体积的液体储存和泵送。
Centrifugal microfluidic platforms have emerged as point-of-care diagnostic tools. However, the unidirectional nature of the centrifugal force limits the available space for multi-stepped processes on a single microfluidics disc. To overcome this limitation, a passive pneumatic pumping method actuated at high rotational speeds has been previously proposed to pump liquid against the centrifugal force. In this paper, a novel micro-balloon pumping method that relies on elastic energy stored in a latex membrane is introduced. It operates at low rotational speeds and pumps a larger volume of liquid towards the centre of the disc. Two different micro-balloon pumping designs have been developed to study the pump performance and capacity at a range of rotational frequencies from 0 to 1500 rpm. The behaviour of the micro-balloon pump on the centrifugal microfluidic platforms has been theoretically analysed and compared with the experimental data. The experimental data shows that, the developed pumping method dramatically decreases the required rotational speed to pump liquid compared to the previously developed pneumatic pumping methods. It also shows that within a range of rotational speed, desirable volume of liquid can be stored and pumped by adjusting the size of the micro-balloon.
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影响因子：
6.1
作者：
Haeberle, Stefan;Brenner, Thilo;Ducree, Jens
通讯作者：
Ducree, Jens
DOI：
10.1016/j.msec.2010.09.007
发表时间：
2011-03-12
影响因子：
7.9
作者：
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通讯作者：
Graeff, Carlos F. O.
影响因子：
8.4
作者：
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通讯作者：
Mathies, RA
影响因子：
6.1
作者：
Cosnier, S;Szunerits, S;Rico-Lattes, I
通讯作者：
Rico-Lattes, I
影响因子：
2.8
作者：
Garcia-Cordero, Jose L.;Basabe-Desmonts, Lourdes;Ricco, Antonio J.
通讯作者：
Ricco, Antonio J.