Association of self-reported snoring with decreased retinal thickness and vessel density.
Association of self-reported snoring with decreased retinal thickness and vessel density.
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自我报告的打鼾与视网膜厚度和血管密度减少的关系
DOI：
10.3389/fphys.2022.917808
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发表时间：
2022
影响因子：
4
通讯作者：
中科院分区：
文献类型：
--
作者：
目的：据报道，自我报告的打鼾会影响神经和血管。然而，很少有直接证据表明打鼾与神经和微血管缺陷有关。因此，我们评估了自我报告的打鼾与视网膜结构和微循环的关联。 方法：冀东眼科队列研究（JECS）共招募 2,622 名参与者。记录体检、实验室测试和问卷调查。我们还使用光学相干断层扫描（OCT）和光学相干断层扫描血管造影（OCTA）来评估视网膜结构和微血管网络。根据自我报告的频率，打鼾被定义为“从不”、“偶尔”和“经常或更严重”。 结果：男性和女性打鼾患病率分别为 84.6% (n = 983) 和 45.0% (n = 657)。与从不打鼾组相比，“偶尔”组（p < 0.001）和“经常或更严重”组（p = 0.001）的视网膜厚度增加，而打鼾组之间没有发现差异（p = 0.14）。 “经常或更严重”打鼾组的浅层视网膜毛细血管丛（RCP）血管密度低于“从不”打鼾组（p < 0.001）和“偶尔”打鼾组（p < 0.001）。调整混杂因素后，“频繁或更严重”打鼾与较薄的视网膜总厚度[β = -2.79 (95% CI: -5.27, -0.30)]和较低的浅表RCP血管密度[β = -0.71 (95% CI: -1.19, -0.23)]显着相关。 结论：我们的研究表明，自我报告的打鼾与较薄的视网膜厚度和较低的浅表 RCP 血管密度有关。我们的研究结果强调需要进行自我报告的打鼾评估来确定视网膜结构和微循环障碍。
Purpose: Self-reported snoring has been reported to influence nerves and vessels. However, there are few direct evidences of snoring related to nerves and microvessels defects. Therefore, we evaluated the association of self-reported snoring with retinal structure and microcirculation. Methods: A total of 2,622 participants were recruited from the Jidong eye cohort study (JECS). Physical examinations, laboratory tests, and questionnaires were recorded. We also used optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) to assess the retinal structure and microvascular network. Snoring was defined as “never,” “occasionally,” and “frequently or more severe” according to self-reported frequency. Results: The prevalence of snoring were 84.6% (n = 983) and 45.0% (n = 657) in males and females, respectively. Compared with never snoring group, the retinal thickness increased in “occasionally” (p < 0.001) and “frequently or more severe” groups (p = 0.001), while no difference was found between snoring groups (p = 0.14). Superficial retinal capillary plexus (RCP) vessel density was lower in “frequently or more severe” group than in “never” (p < 0.001) and “occasionally” snoring groups (p < 0.001). After adjusting for confounders, “frequently or more severe” snoring was significantly associated with thinner total retinal thickness [β = −2.79 (95% CI: −5.27, −0.30)] and lower superficial RCP vessel density [β = −0.71 (95% CI: −1.19, −0.23)]. Conclusion: Our research showed self-reported snoring was associated with thinner retinal thickness and lower superficial RCP vessel density. The findings of our study emphasize the need for self-reported snoring assessments in determining retinal structure and microcirculation impairment.
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影响因子：
3
作者：
Jiang Z;Qin J;Liang K;Zhao R;Yan F;Hou X;Wang C;Chen L
通讯作者：
Chen L
影响因子：
4.7
作者：
Nagayoshi M;Tanigawa T;Yamagishi K;Sakurai S;Kitamura A;Kiyama M;Okada T;Maeda K;Ohira T;Imano H;Sato S;Iso H;CIRCS Investigators
通讯作者：
CIRCS Investigators
影响因子：
5.6
作者：
István L;Czakó C;Élő Á;Mihály Z;Sótonyi P;Varga A;Ungvári Z;Csiszár A;Yabluchanskiy A;Conley S;Csipő T;Lipecz Á;Kovács I;Nagy ZZ
通讯作者：
Nagy ZZ
影响因子：
2.5
作者：
Rosen, David M.;Kundel, Vaishnavi;Shah, Neomi
通讯作者：
Shah, Neomi
影响因子：
4.8
作者：
Brockmann, Pablo E.;Schlaud, Martin;Urschitz, Michael S.
通讯作者：
Urschitz, Michael S.