Current epidemiology of Pneumocystis pneumonia.
Current epidemiology of Pneumocystis pneumonia.
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DOI：
10.3201/eid1010.030985
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发表时间：
2004-10
影响因子：
11.8
通讯作者：
Kaplan JE
中科院分区：
文献类型：
--
作者：
Morris A;Lundgren JD;Masur H;Walzer PD;Hanson DL;Frederick T;Huang L;Beard CB;Kaplan JE
对PCP发病率的变化、PCP的高危人群以及该病的可能趋势进行了讨论。肺孢子虫肺炎(PCP)历来是艾滋病人患病的主要原因之一。工业化国家采用了高效的抗逆转录病毒疗法，使艾滋病相关并发症的发生率急剧下降，包括卡介苗肺炎。在成人人群中，PCP的发病率显著下降，但它仍然是最常见的艾滋病定义感染之一。儿科人口中也出现了类似的下降。在许多发展中国家，五氯苯酚仍然是一个严重的健康问题，尽管其在撒哈拉以南非洲成年人中的发病率一直存在争议。这篇综述讨论了当前艾滋病流行时代的五氯苯酚的流行病学。尽管在工业化国家发生的PCP病例较少，但抗药性艾滋病毒感染的增加、可能的抗药性PCP以及发展中国家数量巨大的艾滋病病例使这种疾病继续具有公共卫生重要性。
Changes in incidence of PCP, groups at risk for PCP, and possible trends in the disease are discussed. Pneumocystis pneumonia (PCP) has historically been one of the leading causes of disease among persons with AIDS. The introduction of highly active antiretroviral therapy in industrialized nations has brought about dramatic declines in the incidence of AIDS-associated complications, including PCP. In the adult population, the incidence of PCP has significantly decreased, but it remains among the most common AIDS-defining infections. Similar declines have been documented in the pediatric population. In much of the developing world, PCP remains a significant health problem, although its incidence among adults in sub-Saharan Africa has been debated. This review discusses the epidemiology of PCP during the current era of the AIDS epidemic. Although fewer cases of PCP occur in industrialized countries, increasing drug-resistant HIV infections, possible drug-resistant PCP, and the tremendous number of AIDS cases in developing countries make this disease of continued public health importance.
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影响因子：
168.9
作者：
MALIN, AS;GWANZURA, LKZ;MASON, PR
通讯作者：
MASON, PR
影响因子：
3.6
作者：
Dankner, WM;Lindsey, JC;Levin, MJ
通讯作者：
Levin, MJ
影响因子：
3.1
作者：
Kattan, M;Platzker, A;Colin, AA
通讯作者：
Colin, AA
影响因子：
3.8
作者：
Detels, R;Tarwater, P;Muñoz, A
通讯作者：
Muñoz, A
影响因子：
5
作者：
KASLOW, RA;OSTROW, DG;RINALDO, CR
通讯作者：
RINALDO, CR