Prevalence of antimicrobial resistance among bacterial pathogens isolated from cattle in different European countries: 2002-2004.
Prevalence of antimicrobial resistance among bacterial pathogens isolated from cattle in different European countries: 2002-2004.
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从不同欧洲国家中分离出的细菌病原体中抗菌素耐药性的患病率：2002- 2004年。
DOI：
10.1186/1751-0147-50-28
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发表时间：
2008-07-08
影响因子：
2.1
通讯作者：
Aarestrup, Frank M.
中科院分区：
文献类型：
--
作者：
Hendriksen, Rene S.;Mevius, Dik J.;Schroeter, Andreas;Teale, Christopher;Meunier, Daniele;Butaye, Patrick;Franco, Alessia;Utinane, Andra;Amado, Alice;Moreno, Miguel;Greko, Christina;Staerk, Katharina;Berghold, Christian;Myllyniemi, Anna-Liisa;Wasyl, Dariusz;Sunde, Marianne;Aarestrup, Frank M.
“动物源性细菌的抗生素耐药性- II”（ARBAO-II）项目由欧盟资助（FAIR 5-QLK 2 -2002-01146），为期2003-2005年，目的是根据经验证和协调的方法，在欧洲国家的兽医实验室中建立对抗生素敏感性的持续监测。收集了不同实验室细菌病原体药敏试验的可用汇总数据。在三年期间（2002-2004年）获得了几种牛病原体的抗菌药物敏感性数据。每年，要求参与实验室在Excel文件模板中填写关于不同细菌种属的抗菌素耐药性发生率的国家汇总数据。每年进行一次抗菌药物敏感性试验的能力测试（EQAS -外部质量保证体系），以测试参与实验室抗菌药物敏感性试验的准确性。该检测的数据表明，对于EQAS中包含的种属，各国之间的结果具有可比性。从13个欧洲国家收集了25，241株分离株的数据。对于来自牛乳房炎的金黄色葡萄球菌，各国之间以及测试的不同抗菌剂之间的耐药性发生率存在明显差异。青霉素耐药频率最高。在法国、荷兰和葡萄牙观察到溶血性曼氏菌对氨苄西林、四环素和甲氧苄啶/磺胺的耐药性。在芬兰分离的所有多杀性巴氏杆菌分离株以及来自丹麦、英格兰（和威尔士）、意大利和瑞典的大多数分离株对大多数抗菌剂敏感。来自瑞典的停乳链球菌和尿链球菌分离株完全敏感。在其他国家，观察到对四环素、庆大霉素和红霉素的一些耐药性。与研究的其他细菌种属相比，观察到大肠埃希菌的耐药性更强，且各国间的耐药性水平存在差异。一般而言，来自丹麦、英格兰（和威尔士）、荷兰、挪威、瑞典和瑞士的分离株耐药频率较低，而来自比利时、法国、意大利、拉脱维亚和西班牙的许多分离株对大多数测试的抗菌剂耐药。将来，耐药性流行率的数据应用于制定兽药中适当使用抗菌剂的指南。
The project "Antibiotic resistance in bacteria of animal origin – II" (ARBAO-II) was funded by the European Union (FAIR5-QLK2-2002-01146) for the period 2003–2005, with the aim to establish a continuous monitoring of antimicrobial susceptibility among veterinary laboratories in European countries based on validated and harmonised methodologies. Available summary data of the susceptibility testing of the bacterial pathogens from the different laboratories were collected. Antimicrobial susceptibility data for several bovine pathogens were obtained over a three year period (2002–2004). Each year the participating laboratories were requested to fill in excel-file templates with national summary data on the occurrence of antimicrobial resistance from different bacterial species. A proficiency test (EQAS – external quality assurance system) for antimicrobial susceptibility testing was conducted each year to test the accuracy of antimicrobial susceptibility testing in the participating laboratories. The data from this testing demonstrated that for the species included in the EQAS the results are comparable between countries. Data from 25,241 isolates were collected from 13 European countries. For Staphylococcus aureus from bovine mastitis major differences were apparent in the occurrence of resistance between countries and between the different antimicrobial agents tested. The highest frequency of resistance was observed for penicillin. For Mannheimia haemolytica resistance to ampicillin, tetracycline and trimethoprim/sulphonamide were observed in France, the Netherlands and Portugal. All isolates of Pasteurella multocida isolated in Finland and most of those from Denmark, England (and Wales), Italy and Sweden were susceptible to the majority of the antimicrobials. Streptococcus dysgalactiae and Streptococcus uberis isolates from Sweden were fully susceptible. For the other countries some resistance was observed to tetracycline, gentamicin and erythromycin. More resistance and variation of the resistance levels between countries were observed for Escherichia coli compared to the other bacterial species investigated. In general, isolates from Denmark, England (and Wales), the Netherlands, Norway, Sweden and Switzerland showed low frequencies of resistance, whereas many isolates from Belgium, France, Italy, Latvia and Spain were resistant to most antimicrobials tested. In the future, data on the prevalence of resistance should be used to develop guidelines for appropriate antimicrobial use in veterinary medicine.
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影响因子：
0.9
作者：
Kaszanyitzky, EJ;Egyed, Z;Somogyi, P
通讯作者：
Somogyi, P
影响因子：
11.8
作者：
Levy, SB
通讯作者：
Levy, SB
影响因子：
3.5
作者：
Rossitto, PV;Ruiz, L;Cullor, JS
通讯作者：
Cullor, JS
影响因子：
9.4
作者：
WATTS, JL;YANCEY, RJ;CASE, CA
通讯作者：
CASE, CA
DOI：
10.1016/s0924-8579(01)00485-x
发表时间：
2002-03-01
影响因子：
10.8
作者：
Guérin-Faublée, V;Tardy, F;Carret, G
通讯作者：
Carret, G