Near-infrared optical-resolution photoacoustic microscopy.

Near-infrared optical-resolution photoacoustic microscopy.
复制标题

DOI:
10.1364/ol.39.005192
复制
发表时间:
2014-09-01
期刊:
影响因子:
3.6
通讯作者:
Wang LV
Wang LV
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
Hai P;Yao J;Maslov KI;Zhou Y;Wang LV

文献摘要

参考文献

被引文献

相似文献

与可见光(380-700 nm)相比,近红外光(700-1400 nm)在生物组织中的光衰减较弱,因此可以穿透得更深。在这里,我们展示了1046 nm光照下的近红外光学分辨率光声显微镜(NIR-OR-PAM)。在ANSI限制范围内(100mJ/cm2),体外鸡胸组织的穿透深度达到3.2 mm。在鸡胸组织中,NIR-OR-PAM的分辨率超过了约0.6 mm,比570 nm的可见光对应物显示出更好的分辨率。NIR-OR-PAM的深度成像能力在小鼠的耳朵和小鼠脑中都得到了验证。并探讨了NIR-或-PAM可能存在的脂质造影剂。
Compared with visible light (380–700 nm), near-infrared light (700–1400 nm) undergoes weaker optical attenuation in biological tissue, thus it can penetrate deeper. Here, we demonstrate near-infrared optical-resolution photoacoustic microscopy (NIR-OR-PAM) with 1046 nm illumination. A penetration depth of 3.2 mm was achieved in chicken breast tissue ex vivo using optical fluence within the ANSI limit (100 mJ/cm2). Beyond ~0.6 mm deep in chicken breast tissue, NIR-OR-PAM has shown finer resolution than the visible counterpart with 570 nm illumination. The deep imaging capability of NIR-OR-PAM was validated in both the mouse ear and mouse brain. NIR-OR-PAM of possible lipid contrast was explored as well.
DOI: 10.1364/ao.12.000555
发表时间: 1973-01-01
期刊: APPLIED OPTICS
影响因子: 1.9
作者:
HALE, GM;QUERRY, MR
通讯作者: QUERRY, MR
DOI: 10.1364/ol.36.000139
发表时间: 2011-01-15
期刊: Optics letters
影响因子: 3.6
作者:
Wang L;Maslov K;Yao J;Rao B;Wang LV
通讯作者: Wang LV
DOI: 10.1117/1.jbo.19.1.016004
发表时间: 2014-01-01
影响因子: 3.5
作者:
Matthews, Thomas Paul;Zhang, Chi;Wang, Lihong V.
通讯作者: Wang, Lihong V.
DOI: 10.1002/lsm.10002
发表时间: 2001-01-01
影响因子: 2.4
作者:
Sato, S;Ogura, M;Ashida, H
通讯作者: Ashida, H
DOI: 10.1117/1.jbo.18.9.096004
发表时间: 2013-09-01
影响因子: 3.5
作者:
Liang, Jinyang;Zhou, Yong;Wang, Lihong V.
通讯作者: Wang, Lihong V.