Bioprinting for the Biologist.

Bioprinting for the Biologist.
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生物学家的生物印刷。

DOI:
10.1016/j.cell.2020.12.002
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发表时间:
2021-01-07
期刊:
影响因子:
64.5
通讯作者:
Burdick, Jason A.
Burdick, Jason A.
中科院分区:
生物学1区
文献类型:
--
作者:
Daly, Andrew C.;Prendergast, Margaret E.;Hughes, Alex J.;Burdick, Jason A.

文献摘要

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从头开始构建组织来探索全新的细胞结构可能会彻底改变生物学的基本理解。生物打印是一种新兴的技术来做到这一点。虽然通常应用于工程组织用于治疗性组织修复或药物筛选,但生物打印在生物学中有许多机会,例如探索细胞串扰或细胞形态发生。本书的总体目标是为生物学家提供生物打印的概述,包括概述挤出生物打印(最广泛使用和最容易获得的技术)的步骤,以及讨论替代生物打印技术和生物打印在生物学中的未来机会。
Building tissues from scratch to explore entirely new cell configurations could revolutionize fundamental understanding in biology. Bioprinting is an emerging technology to do this. Although typically applied to engineer tissues for therapeutic tissue repair or drug screening, there are many opportunities for bioprinting within biology, such as to explore cellular crosstalk or cellular morphogenesis. The overall goal of this Primer is to provide an overview of bioprinting with the biologist in mind, including outlining the steps in extrusion bioprinting (the most widely used and accessible technology), as well as discussing alternative bioprinting technologies and future opportunities for bioprinting in biology.
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