Laser ablation as treatment strategy for medically refractory dominant insular epilepsy: therapeutic and functional considerations.
Laser ablation as treatment strategy for medically refractory dominant insular epilepsy: therapeutic and functional considerations.
复制标题
DOI：
10.1159/000366001
复制
发表时间：
2014
影响因子：
1.7
通讯作者：
Leuthardt EC
中科院分区：
文献类型：
--
作者：
Hawasli AH;Bandt SK;Hogan RE;Werner N;Leuthardt EC
自2008年引入神经外科以来，激光消融技术在很大程度上仅限于治疗不可切除的肿瘤。该技术在成人人群中用于局灶性癫痫管理的应用尚未得到充分探索。鉴于近1，000，000名美国人患有难治性癫痫，目前的手术技术只能解决一小部分癫痫病理，因此需要额外的治疗选择。我们报告一位53岁的男性，以微创激光消融术成功治疗显性岛叶癫痫，并发轻度语言及记忆障碍。我们还报告了该患者术前和消融术后8个月的神经心理学测试数据。该病例代表了首次报告的成功患者结局，即激光消融作为治疗难治性卒中后癫痫的一种有效治疗选择。
Since its introduction to neurosurgery in 2008, laser ablative techniques have been largely confined to the management of unresectable tumors. Application of this technology for the management of focal epilepsy in the adult population has not been fully explored. Given that nearly 1,000,000 Americans live with medically refractory epilepsy and current surgical techniques only address a fraction of epileptic pathologies, additional therapeutic options are needed. We report the successful treatment of dominant insular epilepsy in a 53 year-old male with minimally-invasive laser ablation complicated by mild verbal and memory deficits. We also report neuropsychological test data on this patient before surgery and at 8-months after the ablation procedure. This account represents the first reported successful patient outcome of laser ablation as an effective treatment option for medically refractory post-stroke epilepsy in an adult.
登录
查看更多内容
影响因子：
5.6
作者：
Erba, Giuseppe;Moja, Lorenzo;Pupillo, Elisabetta
通讯作者：
Pupillo, Elisabetta
影响因子：
2.6
作者：
Erba, Giuseppe;Messina, Paolo;Beghi, Ettore
通讯作者：
Beghi, Ettore
影响因子：
2.6
作者：
Curry, Daniel J.;Gowda, Ashok;Wilfong, Angus A.
通讯作者：
Wilfong, Angus A.
影响因子：
2.6
作者：
Helmstaedter, C
通讯作者：
Helmstaedter, C
影响因子：
5.6
作者：
Mohammed, Hussan S.;Kaufman, Christian B.;Smyth, Matthew D.
通讯作者：
Smyth, Matthew D.