Effects of individual ozone exposure on lung function in the elderly: a cross-sectional study in China
Effects of individual ozone exposure on lung function in the elderly: a cross-sectional study in China
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个体臭氧暴露对老年人肺功能的影响:中国的一项横断面研究
DOI:
10.1007/s11356-019-04324-w
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发表时间:
2019-02
影响因子:
5.8
通讯作者:
Xu Yan
中科院分区:
文献类型:
--
作者:
Zhang Jiayao;Sun Hong;Chen Qi;Gu Jie;Ding Zhen;Xu Yan
The aim of this study was to assess the acute health effects of individual ozone (O3) exposure on the respiratory system in the elderly. A total of 40 non-smoking elderly volunteers completed personal 24 h of measurement for O3and fine particulate matter (PM2.5). To assess health effects, we measured the pulmonary function and five inflammatory biomarkers in exhaled breath condensate (EBC), including interleukin-2 (IL-2), interferon-γ (IFN-γ), prostaglandin E2(PGE2), and tumor necrosis factor α/β (TNFα/β). We used the generalized additive model to analyze the association between O3and these health effects, after adjusting PM2.5, BMI, and sex as confounders. As a result, we found a negative correlation between O3and forced vital capacity (FVC) or forced expiratory volume-one second (FEV1). With the increasing of O3by 10 μg/m3, FVC and FEV1 decreased by 0.13 L (95% CI 0.01, 0.26) and 0.11 L (95% CI 0.02, 0.20), respectively. We found no statistical significance between O3and biomarkers in EBC. The results suggested that individual 24-h O3exposure was associated with decreased pulmonary function in the elderly.
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影响因子:
4.7
作者:
Yoda Y;Takagi H;Wakamatsu J;Ito T;Nakatsubo R;Horie Y;Hiraki T;Shima M
通讯作者:
Shima M
影响因子:
2.6
作者:
Stiegel, Matthew A.;Pleil, Joachim D.;Madden, Michael C.
通讯作者:
Madden, Michael C.
影响因子:
1.5
作者:
C. Plopper;S. Smiley-Jewell;L. Miller;M. Fanucchi;M. J. Evans;A. Buckpitt;M. Avdalovic;L. Gershwin-L.-Gers
通讯作者:
C. Plopper;S. Smiley-Jewell;L. Miller;M. Fanucchi;M. J. Evans;A. Buckpitt;M. Avdalovic;L. Gershwin-L.-Gers
影响因子:
3.9
作者:
Cooper, O. R.;Parrish, D. D.;Zbinden, R. M.
通讯作者:
Zbinden, R. M.
DOI:
10.1080/19338244.2014.932753
发表时间:
2015-01-02
影响因子:
1.8
作者:
Kariisa, Mbabazi;Foraker, Randi;Wilkins, J. R., III
通讯作者:
Wilkins, J. R., III