High-Power Ultrasonic Transducer for Effective Hemolysis

High-Power Ultrasonic Transducer for Effective Hemolysis
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高功率超声波换能器可有效溶血

DOI:
10.1109/tuffc.2021.3116977
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发表时间:
2022
期刊:
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
影响因子:
--
通讯作者:
Morita Takeshi
Morita Takeshi
中科院分区:
--
文献类型:
--
作者:
Wu Xiaogang;Chen Kang;Hoshijima Yasushi;Hariu Taro;Yamazaki Hiroki;Miyake Susumu;Morita Takeshi

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为了实现小型化和便携式溶血装置,超声换能器与血液通道的建议,在这项研究中。超声波通过抛物面反射器聚焦,在通道内产生高声压,用于溶血。使用模拟和实验的传感器的溶血性能进行评估。在不同的电压和流量下进行实验,以验证溶血的可行性。在外加电压为80 Vp-p、流速为0.25 mL/min、驱动频率为1.28 MHz时,溶血率大于93%。
To realize compact and portable hemolysis devices, an ultrasonic transducer with a blood channel is proposed in this study. Ultrasound waves are focused by a parabolic reflector to generate high sound pressure inside the channel for hemolysis. The hemolysis performance of the transducer is evaluated using simulations and experiments. Experiments are performed with various voltages and flow rates to verify the feasibility of hemolysis. The hemolysis rate is more than 93% at an applied voltage of 80 Vp-p, a flow rate of 0.25 mL/min, and a driving frequency of 1.28 MHz.
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