Acute psychological stress, autonomic function, and arterial stiffness among women.
Acute psychological stress, autonomic function, and arterial stiffness among women.
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DOI：
10.1016/j.ijpsycho.2020.06.015
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发表时间：
2020-09
期刊：
影响因子：
--
通讯作者：
Annex BH
中科院分区：
文献类型：
--
作者：
Logan JG;Teachman BA;Liu X;Farber CR;Liu Z;Annex BH
本研究旨在探讨急性心理应激对自主神经功能和动脉僵硬度的影响，并检验自主神经功能变化在急性应激和动脉僵硬度之间的中介作用。85名健康成年女性被随机分为实验组和对照组。采用特里尔社会应激试验（Trier Social Stress Test，TSST）诱发急性心理应激。在TSST之前和之后评估自主神经功能（通过心脏阻抗和心率变异性[HRV]的高频[HF]的射血前期[PEP]测量）和动脉硬度（通过颈动脉和股动脉脉搏波速度[cfPWV]和增强指数[AIx]测量）。参与者的平均年龄为28.78（±9.84）岁。在控制年龄、体重指数和收缩压后，与对照组相比，实验组参与者在压力源后cfPWV（p = 0.025）和AIx（p = 0.017）显著增加。然而，在PEP（p = .181）和HF（p = .058）的变化方面没有观察到显著的组间差异。PEP和HF的变化与cfPWV（分别为p = 0.975和p = 0.654）和AIx（分别为p = 0.376和p = 0.323）的变化无关。结果表明，即使是短暂的轻度至中度应激，不会引起自主神经功能的持续变化，仍然可能对动脉僵硬度产生显著的不利影响。动脉僵硬度的变化与自主神经功能的变化无关。未来的实验研究与几个测量点，建议确定不同的影响，压力对自主神经功能和动脉僵硬度。
This study aimed to investigate the effect of acute psychological stress on autonomic function and arterial stiffness, and to test a mediating role of changes in autonomic function between acute stress and arterial stiffness. Eighty-five healthy female adults were randomized into either an experimental or control group. The Trier Social Stress Test (TSST) was used to induce acute psychological stress. Autonomic function (measured by pre-ejection period [PEP] from cardiac impedance and high frequency [HF] of heart rate variability [HRV]) and arterial stiffness (measured by carotid and femoral pulse wave velocity [cfPWV] and augmentation index [AIx]) were assessed before and after the TSST. The mean age of the participants was 28.78 (±9.84) years old. Experimental group participants had a significant increase in cfPWV (p = .025) and AIx (p = .017) following the stressor, compared with those in the control group, after controlling for age, body mass index, and systolic blood pressure. However, no significant group differences were observed in changes in PEP (p = .181) and HF (p = .058). Changes in PEP and HF were neither associated with changes in cfPWV (p = .975 and p = .654, respectively), nor in AIx (p = .376 and p = .323, respectively). The results suggest that even a brief period of mild to moderate stress, which does not cause sustainable changes in autonomic function, may still exert significant adverse effects on arterial stiffness. The changes in arterial stiffness were not related to changes in autonomic function. Future experimental studies with several measurement points are recommended to identify distinct effects of stress on autonomic function and arterial stiffness.
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影响因子：
1.6
作者：
Cecelja M;Chowienczyk P
通讯作者：
Chowienczyk P
影响因子：
3.2
作者：
Kalfon, Roy;Campbell, Jeremiah;Figueroa, Arturo
通讯作者：
Figueroa, Arturo
影响因子：
5
作者：
KANSE, SM;TAKAHASHI, K;BLOOM, SR
通讯作者：
BLOOM, SR
影响因子：
5.8
作者：
Licht, Carmilla M. M.;de Geus, Eco J. C.;Penninx, Brenda W. J. H.
通讯作者：
Penninx, Brenda W. J. H.
影响因子：
8.3
作者：
Liao, DP;Arnett, DK;Heiss, G
通讯作者：
Heiss, G