Quantitative magnetic resonance arthrography in patients with femoroacetabular impingement.

Quantitative magnetic resonance arthrography in patients with femoroacetabular impingement.
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DOI:
10.1002/jmri.25314
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发表时间:
2016-12
影响因子:
4.4
通讯作者:
Majumdar, Sharmila
Majumdar, Sharmila
中科院分区:
医学2区
文献类型:
--
作者:
Samaan, Michael A.;Zhang, Alan L.;Gallo, Matthew C.;Schwaiger, Benedikt J.;Link, Thomas M.;Souza, Richard B.;Majumdar, Sharmila

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具有 T1ρ 和 T2 映射等序列的髋部定量磁共振成像 (QMRI) 已被用来检测软骨基质成分的早期变化。然而,QMRI 尚未在关节内造影剂存在的情况下进行。因此,本研究的目的是评估 QMRI 在股骨髋臼撞击 (FAI) 患者的 MR 关节造影 (MRA) 过程中的可行性和使用。使用 3T MR 扫描仪,10 名 FAI 患者接受了髋关节的单侧 MRA 和标准 MRI。在 MRA 和 MRI 评估中计算髋臼和股骨关节软骨的全局和次区域 T1ρ 和 T2 弛豫时间,并使用 Krippendorff α (α) 系数和线性回归 (μ) 评估这些值的一致性。使用重复测量方差分析比较 MRA 和 MRI 之间的 T1ρ 和 T2 弛豫时间。全局和次区域 T1ρ 和 T2 弛豫时间均表现出很强的一致性(α>0.83;μ>0.85),与关节内对比度无关。此外,MRA 和 MRI 之间的整体和次区域髋臼 T1ρ (p=0.72) 和 T2 (p=0.94) 以及股骨 T1ρ、松弛时间相似 (p=0.73),但使用关节内造影剂时股骨 T2 松弛时间减少 (p=0.04)。这项研究证明了 T1ρ 和 T2 映射用于 FAI 患者髋部 MRA 的可行性。 MRA 中纳入 QMRI 可以定量评估 FAI 对髋关节软骨的影响,同时允许使用关节内造影剂对盂唇病理进行详细评估。
Quantitative magnetic resonance imaging (QMRI) of the hip with sequences such as T1ρ and T2 mapping has been utilized to detect early changes in cartilage matrix composition. However, QMRI has not been performed in the presence of intra-articular contrast. Thus the purpose of this study was to evaluate the feasibility and use of QMRI during MR-arthrography (MRA) in femoracetabular impingement (FAI) patients. Using a 3T MR-scanner, ten FAI patients underwent a unilateral MRA and standard MRI of the hip joint. Global and sub-regional T1ρ and T2 relaxation times of the acetabular and femoral articular cartilage were computed in the MRA and MRI assessments and agreement of these values were assessed using the Krippendorff’s alpha (α) coefficient and linear regression (μ). T1ρ and T2 relaxation times between the MRA and MRI were compared using a repeated measures analysis of variance. Both global and sub-regional T1ρ and T2 relaxation times demonstrated strong agreement (α>0.83; μ>0.85) independent of intra-articular contrast. Also, global and sub-regional acetabular T1ρ (p=0.72) and T2 (p=0.94), as well as femoral T1ρ, relaxation times were similar between MRA and MRI (p=0.73) yet femoral T2 relaxation times decreased when using intra-articular contrast (p=0.04). This study demonstrated the feasibility of T1ρ and T2 mapping for use in hip MRA with FAI patients. The inclusion of QMRI in MRA provides a quantitative assessment of the effects of FAI on hip joint articular cartilage while allowing for detailed assessment of labral pathology with the use of intra-articular contrast.
DOI: 10.1097/01.blo.0000096804.78689.c2
发表时间: 2003-12-01
影响因子: 4.2
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Ganz, R;Parvizi, J;Siebenrock, KA
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