The Role of Dendritic Cells in the Differentiation of T Follicular Helper Cells.
The Role of Dendritic Cells in the Differentiation of T Follicular Helper Cells.
复制标题
树突状细胞在滤泡辅助 T 细胞分化中的作用
DOI:
10.1155/2018/7281453
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发表时间:
2018
影响因子:
4.1
通讯作者:
Yang W
中科院分区:
文献类型:
--
作者:
Zou X;Sun G;Huo F;Chang L;Yang W
T follicular helper cells (TFH) are a subset of recently discovered CD4+T cells. Their major function is to participate in the formation of germinal centres (GCs) and promote B cell proliferation and differentiation to play important roles in the production of antibodies. Currently, the functions of TFHcells are clear. However, the early differentiation of these cells is not clear. Dendritic cells (DCs) participate in the differentiation of TFHcells. Therefore, this article reviewed the research progress regarding the influence of DCs on the differentiation of TFHcells and their major underlying mechanisms.
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影响因子:
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