Gender disparity in pediatrics: a review of the current literature.
Gender disparity in pediatrics: a review of the current literature.
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DOI：
10.1186/s13052-017-0437-x
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发表时间：
2018-01-02
影响因子：
3.6
通讯作者：
de Martino M
中科院分区：
文献类型：
--
作者：
Piccini P;Montagnani C;de Martino M
基于性别的医学是生物医学研究的一个创新分支，代表了未来健康研究的新视角。已经发表了许多关于成人性别医学的研究，但关于儿童的数据很少。使用Pubmed数据库中的多个关键词和标准化术语，对2006年7月1日至2017年2月1日期间发表的仅涉及儿童的文献进行了文献检索。检索仅限于英文出版物。对内分泌、神经、精神、胃肠道、免疫、肿瘤、风湿、呼吸系统疾病、感染性疾病和镇痛的所有相关文章进行了评价，并将相关文章纳入本综述。关于儿童期性别差距的现有研究大多数是关于内分泌和神经精神疾病的，而其他医学领域的数据很少。即使可以在文献中找到一些关于儿科性别差异的研究，也很少有人进一步分析所观察到的差异的原因。目前尚没有关于男女儿童药代动力学和药效学差异的数据，因此，应在儿童期进行更多的研究。
Gender-based medicine is an innovative branch of biomedical research and represents a new perspective for the future of health research. Many studies have been published on gender medicine in adults but very few data regarding children are available. A literature search covering articles published between 1stJuly, 2006 and 1st February, 2017 and concerning children only was conducted using multiple keywords and standardized terminology in Pubmed database. The search was limited to English-language publications. All relevant articles on endocrines, neurological, psychiatric, gastrointestinal, immunological, oncological, rheumatic, pneumological disorders, infectious diseases and analgesia were evaluated and pertinent articles were included in this review. Most of the available studies on gender disparity in childhood are about endocrine and neuro-psychiatric disorders, while there are few data in other areas of medicine. Even if several studies on pediatric gender differences can be found on literature, few of them move forwards to analyze the reasons of the observed diversity. No data on pharmacokinetic and pharmacodynamic differences between boys and girls can be found. Hence, more efforts should be directed to investigate these topics in childhood.
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影响因子：
2.3
作者：
Leiter, Valerie;Rieker, Patricia P.
通讯作者：
Rieker, Patricia P.
影响因子：
3.7
作者：
Jang Y;Shin A
通讯作者：
Shin A
影响因子：
3.1
作者：
Lang, Jason E.;Holbrook, Janet T.;Wise, Robert A.;Dixon, Anne E.;Teague, W. Gerald;Wei, Christine Y.;Irvin, Charles G.;Shade, David;Lima, John J.
通讯作者：
Lima, John J.
影响因子：
3.2
作者：
Curran, Emily K.;Sainani, Kristin L.;Fisher, Paul G.
通讯作者：
Fisher, Paul G.
DOI：
10.1097/01.qai.0000164247.49098.0e
发表时间：
2005-12-01
影响因子：
3.6
作者：
Galli, L;Puliti, D;de Martino, M
通讯作者：
de Martino, M