Human toxoplasmosis in Mozambique: gaps in knowledge and research opportunities.
Human toxoplasmosis in Mozambique: gaps in knowledge and research opportunities.
复制标题
DOI:
10.1186/s13071-020-04441-3
复制
发表时间:
2020-11-11
影响因子:
3.2
通讯作者:
Noormahomed EV
中科院分区:
文献类型:
--
作者:
Manuel L;Santos-Gomes G;Noormahomed EV
Toxoplasmosis is a parasitic zoonotic disease caused by Toxoplasma gondii that afflicts humans worldwide and wild and domestic warm-blooded animals. In immunocompetent individuals, the acute phase of infection presents transient low or mild symptoms that remain unnoticed. In immunocompromised patients, T. gondii is a life-threatening opportunistic infection, which can result from the reactivation of latent infection or primary infection. Moreover, congenital toxoplasmosis, which results from the transplacental passage of tachyzoites into the fetus during a pregnant primary infection, can lead to miscarriage, stillbirth, or ocular and neurologic disease, and neurocognitive deficits in the newborns. Thus, the present review aims to address the current knowledge of T. gondii infection and toxoplasmosis in Africa and especially in Mozambique, stressing the importance of identifying risk factors and promote awareness among the health care providers and population, assessing the gaps in knowledge and define research priorities. In Mozambique, and in general in southern African countries, clinical disease and epidemiological data have not yet been entirely addressed in addition to the implications of T. gondii infection in immunocompetent individuals, in pregnant women, and its relation with neuropsychiatric disorders. The main gaps in knowledge in Mozambique include lack of awareness of the disease, lack of diagnostic methods in health facilities, lack of genetic data, and lack of control strategies.
登录
查看更多内容
影响因子:
3.6
作者:
Dos Santos PF;Wainberg ML;Caldas-de-Almeida JM;Saraceno B;Mari Jde J
通讯作者:
Mari Jde J
影响因子:
4.6
作者:
Deng H;Devleesschauwer B;Liu M;Li J;Wu Y;van der Giessen JWB;Opsteegh M
通讯作者:
Opsteegh M
影响因子:
--
作者:
Alvarado-Esquivel C;Rascón-Careaga A;Hernández-Tinoco J;Corella-Madueño MA;Sánchez-Anguiano LF;Aldana-Madrid ML;Velasquez-Vega E;Quizán-Plata T;Navarro-Henze JL;Badell-Luzardo JA;Gastélum-Cano JM;Liesenfeld O
通讯作者:
Liesenfeld O
DOI:
10.1590/s1678-9946201759063
发表时间:
2017-08-24
影响因子:
1.9
作者:
Rezende HHA;Storchilo HR;Lima JAS;Gomes AR Júnior;Gomes TC;Souza JY;Avelino MM;Amaral WND;Vinaud MC;Castro AM
通讯作者:
Castro AM
影响因子:
2.8
作者:
Domingos, Abilio;Ito, Lucy Sayuri;Ramos, Alberto Novaes, Jr.
通讯作者:
Ramos, Alberto Novaes, Jr.