Impact of Metabolic Syndrome on the Mortality Rate among Participants in a Specific Health Check and Guidance Program in Japan.
Impact of Metabolic Syndrome on the Mortality Rate among Participants in a Specific Health Check and Guidance Program in Japan.
复制标题
DOI：
10.2169/internalmedicine.4975-20
复制
发表时间：
2020-11-01
期刊：
影响因子：
--
通讯作者：
Watanabe T
中科院分区：
文献类型：
--
作者：
Iseki K;Konta T;Asahi K;Yamagata K;Fujimoto S;Tsuruya K;Narita I;Kasahara M;Shibagaki Y;Moriyama T;Kondo M;Iseki C;Watanabe T
在日本，2008年启动了专门的健康检查和指导(tokutei-Kenshin)计划，以减轻与代谢综合征(METS)相关的社会负担。然而，到目前为止，还没有发现这一计划对死亡率有任何影响。受试者包括2008至2015年间在七个地区参加过Tokutei-Kenshin的个人。使用国家死亡证明数据库，我们确定了可能已经死亡的人，然后在地区国家健康保险机构和公共卫生护士的合作下进一步确认了这些死亡。METS的诊断依据日本标准。死因按ICD-10进行分类。在调整了年龄、性别、吸烟、饮酒和既往病史(如中风、心脏病和肾脏疾病)后，对死亡风险进行了评估。在总共664,926名受试者中，我们确定了截至2015年底的8,051例死亡病例。METS患者的粗死亡率为1.6%，有初步代谢综合征的患者为1.3%，未患METS的患者为1.1%。在METS中，所有原因的调整风险比(95%可信区间)为1.08(1.02-1.15)，心血管疾病死亡率的调整风险比(95%可信区间)为1.39(1.22-1.58)。研究发现，患有METS的参与者的死亡率要高得多。
In Japan, the Specific Health Check and Guidance (Tokutei-Kenshin) program was started in 2008 to decrease the social burden related to metabolic syndrome (MetS). However, so far this program has not been found to have any impact on the mortality rate. The subjects consisted of individuals who participated in the Tokutei-Kenshin in seven districts between 2008 and 2015. Using a National database of death certificates, we identified those who might have died and then further confirmed such deaths with the collaboration of the regional National Health Insurance agency and public health nurses. The diagnosis of MetS was made according to the Japanese criteria. The causes of death were classified by ICD-10. Mortality risk was evaluated after adjusting for age, sex, smoking, alcohol intake and past medical history such as stroke, heart disease and kidney disease. Among the total of 664,926 subjects, we identified 8,051 fatal cases by the end of 2015. The crude death rate was 1.6% for those with MetS, 1.3% for those with preliminary metabolic syndrome, and 1.1% those without MetS. In MetS, the adjusted hazard ratio (95% confidence interval) was 1.08 (1.02-1.15) for all-cause and 1.39 (1.22-1.58) for cardiovascular disease mortality when the reference was for those without MetS. The death rate was found to be significantly higher among the participants with MetS.
登录
查看更多内容
影响因子：
2.3
作者：
Sato, Yuji;Fujimoto, Shouichi;Watanabe, Tsuyoshi
通讯作者：
Watanabe, Tsuyoshi
在糖尿病，前糖尿病前期或正常葡萄糖耐受性的受试者中，高脉压与蛋白尿的缔合在大型日本总体样本中。
影响因子：
16.2
作者：
Yano Y;Sato Y;Fujimoto S;Konta T;Iseki K;Moriyama T;Yamagata K;Tsuruya K;Yoshida H;Asahi K;Kurahashi I;Ohashi Y;Watanabe T
通讯作者：
Watanabe T
DOI：
10.2169/internalmedicine.56.8006
发表时间：
2017
期刊：
Internal medicine (Tokyo, Japan)
影响因子：
--
作者：
Wakasugi M;Kazama J;Narita I;Iseki K;Fujimoto S;Moriyama T;Yamagata K;Konta T;Tsuruya K;Asahi K;Kondo M;Kurahashi I;Ohashi Y;Kimura K;Watanabe T
通讯作者：
Watanabe T
影响因子：
16.2
作者：
Ford, ES
通讯作者：
Ford, ES
影响因子：
1.5
作者：
Kohro, Takahide;Furui, Yuji;Nagai, Ryozo
通讯作者：
Nagai, Ryozo