Clinical Implications of Exosomes: Targeted Drug Delivery for Cancer Treatment.
Clinical Implications of Exosomes: Targeted Drug Delivery for Cancer Treatment.
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DOI:
10.3390/ijms22105278
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发表时间:
2021-05-17
影响因子:
5.6
通讯作者:
Hafeez BB
中科院分区:
文献类型:
--
作者:
Massey AE;Malik S;Sikander M;Doxtater KA;Tripathi MK;Khan S;Yallapu MM;Jaggi M;Chauhan SC;Hafeez BB
Exosomes are nanoscale vesicles generated by cells for intercellular communication. Due to their composition, significant research has been conducted to transform these particles into specific delivery systems for various disease states. In this review, we discuss the common isolation and loading methods of exosomes, some of the major roles of exosomes in the tumor microenvironment, as well as discuss recent applications of exosomes as drug delivery vessels and the resulting clinical implications.
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