Home kitchen ventilation, cooking fuels, and lung cancer risk in a prospective cohort of never smoking women in Shanghai, China.

Home kitchen ventilation, cooking fuels, and lung cancer risk in a prospective cohort of never smoking women in Shanghai, China.
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DOI:
10.1002/ijc.29020
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发表时间:
2015-02-01
影响因子:
6.4
通讯作者:
Lan, Qing
Lan, Qing
中科院分区:
医学1区
文献类型:
--
作者:
Kim, Christopher;Gao, Yu-Tang;Xiang, Yong-Bing;Barone-Adesi, Francesco;Zhang, Yawei;Hosgood, H. Dean;Ma, Shuangge;Shu, Xiao-ou;Ji, Bu-Tian;Chow, Wong-Ho;Seow, Wei Jie;Bassig, Bryan;Cai, Qiuyin;Zheng, Wei;Rothman, Nathaniel;Lan, Qing

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在发展中国家和农村国家进行的回顾性病例对照研究发现,烹饪引起的室内空气污染与肺癌风险有关。我们报告了上海发达城市人口中烹饪条件、燃料使用、油使用与肺癌风险的关联。从1996年到2009年,共有71320名从不吸烟的女性被跟踪调查,其中429例肺癌病例被确定。问卷收集了这些妇女最近三个住所的家庭生活和烹饪习惯、烹饪燃料和油的使用情况以及通风条件的信息。Cox比例风险回归估计了厨房通风条件、烹饪燃料和食用油使用与肺癌风险的关联,风险比(HR)为95%置信区间(95% CI)。与从不通风不良的厨房相比,通风不良的厨房患肺癌的风险增加49% (HR: 1.49; 95% CI: 1.15-1.95)。曾经使用过煤炭并没有显著关联。然而,与不接触煤炭或通风不良相比,通风不良的煤炭使用(HR: 1.69; 95% CI: 1.22-2.35)和20年或更长时间的煤炭使用(HR: 2.03; 95% CI: 1.35-3.05)显著相关。食用油的使用没有显著相关性。这些结果表明,燃煤通风不良导致的IAP增加了肺癌的风险,这是中国城市中一个重要的公共卫生问题,因为人们可能生活在厨房通风不足的家庭中。
Indoor air pollution (IAP) caused by cooking has been associated with lung cancer risk in retrospective case-control studies in developing and rural countries. We report the association of cooking conditions, fuel use, oil use and risk of lung cancer in a developed urban population in a prospective cohort of women in Shanghai. A total of 71,320 never smoking women were followed from 1996 through 2009 and 429 incident lung cancer cases were identified. Questionnaires collected information on household living and cooking practices for the women’s three most recent residences and utilization of cooking fuel and oil, and ventilation conditions. Cox proportional hazards regression estimated the association for kitchen ventilation conditions, cooking fuels, and use of cooking oils for the risk of lung cancer by hazard ratios (HR) with 95% confidence intervals (95% CI). Ever poor kitchen ventilation was associated with a 49% increase in lung cancer risk (HR: 1.49; 95% CI: 1.15–1.95) compared to never poor ventilation. Ever use of coal was not significantly associated. However, ever coal use with poor ventilation (HR: 1.69; 95% CI: 1.22–2.35) and twenty or more years of using coal (HR: 2.03; 95% CI: 1.35–3.05) was significantly associated compared to no exposure to coal or poor ventilation. Cooking oil use was not significantly associated. These results demonstrate that IAP from poor ventilation of coal combustion increases the risk of lung cancer and is an important public health issue in cities across China where people may have lived in homes with inadequate kitchen ventilation.
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