Visceral adiposity index is associated with lung function impairment: a population-based study.
Visceral adiposity index is associated with lung function impairment: a population-based study.
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内脏肥胖指数与肺功能损伤相关：一项基于人群的研究
DOI：
10.1186/s12931-020-01599-3
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发表时间：
2021-01-06
影响因子：
5.8
通讯作者：
Qin L
中科院分区：
文献类型：
--
作者：
He S;Yang J;Li X;Gu H;Su Q;Qin L
内脏脂肪对肺功能下降的影响已引起广泛关注。最近，内脏脂肪指数（VAI）已被提出作为内脏脂肪分布和功能障碍的标志物。然而，VAI与肺功能之间的关系尚未研究。本研究的目的是分析VAI与肺功能之间的关系，并评估VAI作为肺功能预测因子的潜力。我们从一项基于人群的研究中收集了1786名40岁或以上受试者的数据。所有受试者完成了一份问卷，并进行了人体测量和实验室检查。线性和逻辑回归模型被开发来评估VAI和肺功能之间的关联。男性VAI与FVC%预测值呈负相关，女性VAI与FVC%预测值和FEV1%预测值呈负相关。在线性回归分析中，VAI每增加10%，男性FVC%预测值下降1.127%，女性下降1.943%; VAI每增加10%，男性FEV1%预测值下降0.663%，女性下降1.738%。进一步回归分析显示，女性VAI与FVC和FEV 1受损呈正相关。我们首次在中国人群中显示了VAI与肺功能损害之间的明确相关性。在日常实践中，VAI可能是一种简单可靠的方法，个人，特别是VAI高的女性，应该接受额外的呼吸道疾病筛查和预防干预。
The effects of visceral adiposity on decreased lung function have drawn much attention. Recently, the visceral adiposity index (VAI) has been proposed as a visceral fat distribution and dysfunction marker. However, the relationship between the VAI and lung function has not been investigated. The objective of the study was to analyze the association between the VAI and lung function and evaluate the potential of VAI as a predictor of lung function. We collected data from a population-based study of 1786 subjects aged 40 years or older. All subjects completed a questionnaire and underwent anthropometric measurements and laboratory tests. Linear and logistic regression models were developed to assess the association between the VAI and lung function. The VAI was inversely related to FVC%predicted in men and negatively associated with both FVC%predicted and FEV1%predicted in women. In the linear regression analysis, the decrease in FVC%predicted associated with each 10% increase in the VAI was 1.127% in men and 1.943% in women; the decrease in FEV1%predicted associated with each 10%increase in the VAI was 0.663% in men and 1.738% in women. Further regression analysis revealed that the VAI was positively correlated with FVC and FEV1 impairment in women. We were the first to show a clear correlation between the VAI and lung function impairment in the Chinese population. The VAI could be a simple and reliable approach in daily practice, and individuals, especially women with a high VAI, should receive additional screening and preventive interventions for respiratory disease.
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影响因子：
3.1
作者：
Huang, Liqian;Ye, Ziliang;Liu, Peng
通讯作者：
Liu, Peng
影响因子：
4.5
作者：
Park YS;Kwon HT;Hwang SS;Choi SH;Cho YM;Lee J;Yim JJ
通讯作者：
Yim JJ
影响因子：
8
作者：
Derezinski, Tadeusz;Zozulinska-Ziolkiewicz, Dorota;Dabrowski, Mariusz
通讯作者：
Dabrowski, Mariusz
影响因子：
7.8
作者：
He, Hongbo;Ni, Yinxing;Zhu, Zhiming
通讯作者：
Zhu, Zhiming
影响因子：
8.9
作者：
Ibrahim, M. Mohsen
通讯作者：
Ibrahim, M. Mohsen