Dynamic real-time architecture in magnetic resonance coronary angiography--a prospective clinical trial.

Dynamic real-time architecture in magnetic resonance coronary angiography--a prospective clinical trial.
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磁共振冠状动脉造影中的动态实时架构——一项前瞻性临床试验。

DOI:
10.1081/jcmr-200036192
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发表时间:
2004
期刊:
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子:
--
通讯作者:
Hu,BobS
Hu,BobS
中科院分区:
--
文献类型:
--
作者:
Yang,PhillipC;Santos,JuanM;Nguyen,PatriciaK;Scott,GreigC;Engvall,Jan;McConnell,MichaelV;Wright,GrahamA;Nishimura,DwightG;Pauly,JohnM;Hu,BobS

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ObjectivesA dynamic real‐time (dRT) architecture has been developed to address limitations in magnetic resonance coronary angiography (MRCA). A prospective clinical trial of 45 patients suspected of coronary artery disease was conducted to determine clinical utility of this integrated real‐time system.BackgroundClinical implementation of MRCA is not performed routinely today. However, improved anatomic coverage, image quality, and scan flexibility may enhance its clinical utility. A novel real‐time architecture addresses these challenges through instantaneous reconfiguration between real‐time (RT) and high‐resolution (HR) imaging sequences with dynamic selection of the desired element on a custom‐designed receiver coil.MethodsA total of 45 subjects were recruited consecutively to evaluate scan time, anatomic coverage, image quality, and detection of coronary lesions. Using a modern PC, thedRT switches from RT to gated HR imaging sequence in one repetition time (39 ms). Magnetic resonance imaging (MRI) scanning was performed using a custom‐designed coronary coil consisting of two four‐inch phase‐array circular elements enabled with real‐time selection of the desired coil element.ResultsAll studies were completed in less than 45 minutes and required a mean of 12 breath holds (16 heartbeats). Of the total number of coronary segments, 91% (357/394) were visualized. Excellent or good image quality was achieved in 86% of the segments. Blinded analysis of the coronary arteries revealed sensitivity of 93% and specificity of 88% in the detection of coronary stenoses.ConclusionsThe integrated environment of dRT provides a rapid and flexible scan protocol for MRCA while achieving wide anatomical coverage, high image quality, and reliable detection of coronary stenosis in short scan time.
DOI: 10.1037//0022-3514.48.6.1398
发表时间: 1985
影响因子: 7.6
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通讯作者: Jacobson,NS
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