Enhanced root planing and systemic metronidazole administration improve clinical and microbiological outcomes in a two-step treatment procedure.
Enhanced root planing and systemic metronidazole administration improve clinical and microbiological outcomes in a two-step treatment procedure.
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加强根面平整和全身甲硝唑给药可在两步治疗过程中改善临床和微生物学结果。
DOI：
10.1902/jop.2005.76.6.991
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发表时间：
2005
影响因子：
4.3
通讯作者：
E. Glockmann
中科院分区：
文献类型：
--
作者：
B. Sigusch;A. Güntsch;A. Pfitzner;E. Glockmann
背景
最近，我们描述了一种非手术两步治疗概念，其中我们区分了第一个洁治和根面平整步骤（SRP）和额外的第二个增强根面平整步骤（ERP）。到目前为止，很难确定在ERP期间应多久对根面进行一次仪器测量。
方法
本研究的目的是调查37例侵袭性牙周炎患者在ERP期间进行不同强度的根面平整后的结果。在ERP期间进行全口根面平整。根据每个根面的刮匙敲击次数（器械频率，IF）和探测深度，将患者随机分配到两种根面平整方案之一（第1组，N = 12，第2组，N = 11）。第一组：PD 1至3.5 mm，4 IF（第2组，8 IF）; PD 4至6 mm，8 IF（第2组，14 IF）; PD 6.5至9 mm，12 IF（第2组，20 IF）;和PD >9 mm，16 IF（第2组，24 IF）。第3组患者（对照组; N = 14）仅接受初始SRP。所有三组均接受相同的连续全身抗生素治疗。
结果
在所有组中，结果显示，与基线数据相比，6个月和24个月后PD和临床依恋水平（CAL）存在统计学显著差异。与对照组相比，在第1组和第2组中观察到PD显著降低。第2组（IF较高）的平均PD降低明显更大。此外，牙龈卟啉单胞菌（Pg）和伴放线放线杆菌（Aa）在第2组中在24个月后被完全抑制。
结论
目前的研究结果表明，根面平整的程度对治疗结果有明显的影响。使用最高内固定频率治疗的患者显示出最佳的长期结果。
BACKGROUND
Recently we described a non-surgical two-step treatment concept, in which we distinguished between a first scaling and root planing step (SRP) and an additional second enhanced root planing step (ERP). Until now it is difficult to determine how often a root surface should be instrumented during ERP.
METHODS
The aim of the present study was to investigate the outcomes after different root planing intensities during ERP in 37 patients with aggressive periodontitis after SRP. During ERP a full-mouth root planing was performed. The patients were randomly assigned to one of two root planing regimens (group 1, N = 12 and group 2, N = 11), based on number of curet strokes per root surface (instrumentation frequency, IF) and probing depth. Group 1: PD 1 to 3.5 mm, 4 IF (for group 2, 8 IF); PD 4 to 6 mm, 8 IF (group 2, 14 IF); PD 6.5 to 9 mm, 12 IF (group 2, 20 IF); and PD >9 mm, 16 IF (group 2, 24 IF). Group 3 patients (controls; N = 14) received only the initial SRP. All three groups received the same adjunctive systemic antibiotic treatment.
RESULTS
In all groups, the results showed statistically significant differences in PD and clinical attachment level (CAL) after 6 and 24 months compared to baseline data. Compared with the controls, a significant reduction in PD was observed in groups 1 and 2. The reduction in mean PD was distinctly greater in group 2 (higher IF). Furthermore, Porphyromonas gingivalis (Pg) and Actinobacillus actinomycetemcomitans (Aa) were completely suppressed in group 2 after 24 months.
CONCLUSIONS
The present results show that the extent of root planing has a distinct influence on treatment outcomes. Patients treated with the highest instrumentation frequency showed the best long-term results.
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甲硝唑治疗牙周炎V：清创术应先于药物治疗。
DOI：
--
发表时间：
1994
期刊：
Compendium (Newtown, Pa.)
影响因子：
--
作者：
Loesche,WJ;Giordano,JR
通讯作者：
Giordano,JR
全身抗生素治疗复发性牙周炎患者的效果。
影响因子：
6.7
作者：
Serino,G;Rosling,B;Ramberg,P;Hellström,MK;Socransky,SS;Lindhe,J
通讯作者：
Lindhe,J
影响因子：
4.3
作者：
ADRIAENS, PA;DEBOEVER, JA;LOESCHE, WJ
通讯作者：
LOESCHE, WJ
影响因子：
18.6
作者：
Haffajee, A D;Socransky, S S
通讯作者：
Socransky, S S
牙周根面平整术对牙本质通透性的影响。
影响因子：
6.7
作者：
Fogel,HM;Pashley,DH
通讯作者：
Pashley,DH