REM-dependent repair of competitive memory suppression.

REM-dependent repair of competitive memory suppression.
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DOI:
10.1007/s00221-010-2242-2
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发表时间:
2010-06
影响因子:
2
通讯作者:
Spencer, Rebecca M. C.
Spencer, Rebecca M. C.
中科院分区:
医学4区
文献类型:
--
作者:
Baran, Bengi;Wilson, Jessica;Spencer, Rebecca M. C.

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在睡眠期间,记忆通过记忆巩固过程得到增强。最近的一项研究报道,在没有睡眠依赖的目标记忆巩固的情况下,睡眠增加了竞争性遗忘(Racsmany等人,Psychol Sci 21:80-85,2010)。在这里,使用一个修改后的检索引起的遗忘任务,我们研究了是否睡眠依赖性调制的遗忘同时发生的巩固相关的目标记忆。参与者编码一个词对列表,然后练习检索这些对的一部分。在睡眠或清醒休息后,测试所有配对的回忆。正如预期的那样,相对于清醒,练习过的配对在睡眠后的回忆更好。与Racsmany等人(Psychol Sci 21:80-85,2010)相反,竞争性遗忘在睡眠后减少。此外,回忆练习对与慢波睡眠(SWS),而遗忘的竞争目标负相关的REM,这表明一个新的功能,这些顺序的大脑状态的记忆处理。
Memories are enhanced during sleep through memory consolidation processes. A recent study reported that sleep increases competitive forgetting in the absence of sleep-dependent consolidation of the target memory (Racsmany et al. in Psychol Sci 21:80–85, 2010). Here, using a modified retrieval-induced forgetting task, we examined whether sleep-dependent modulation of forgetting occurs concurrently with the consolidation of related target memories. Participants encoded a word-pair list and then practiced retrieving a portion of these pairs. Following a break with sleep or wake, recall of all pairs was tested. As expected, recall for practiced pairs was greater following sleep relative to wake. Contrary to Racsmany et al. (Psychol Sci 21:80–85, 2010), competitive forgetting decreased following sleep. Moreover, recall for practiced pairs correlated with slow wave sleep (SWS) while forgetting of competing targets correlated negatively with REM, suggesting a novel function of these sequential brain states on memory processing.
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