Intracortical multiplication of thalamocortical signals in mouse auditory cortex.
Intracortical multiplication of thalamocortical signals in mouse auditory cortex.
复制标题
DOI:
10.1038/nn.3493
复制
发表时间:
2013-09
影响因子:
25
通讯作者:
Zhang, Li I.
中科院分区:
文献类型:
--
作者:
Li, Ling-yun;Li, Ya-tang;Zhou, Mu;Tao, Huizhong W.;Zhang, Li I.
Cortical processing of sensory information initiates from the transformation of thalamically-relayed signals. By optogenetically silencing intracortical circuits to isolate thalamic inputs to layer 4 neurons, we show that intracortical excitation linearly amplifies thalamocortical responses underlying frequency and direction selectivity with preserved spectral range and tuning, and prolongs the response duration. This signal pre-amplification and prolongation enhances the salience of thalamocortically-relayed information and ensures its robust, faithful and more persistent representation.
登录
查看更多内容
影响因子:
64.8
作者:
Olsen, Shawn R.;Bortone, Dante S.;Adesnik, Hillel;Scanziani, Massimo
通讯作者:
Scanziani, Massimo
DOI:
10.1523/jneurosci.6220-10.2011
发表时间:
2011-04-06
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
Zhang M;Liu Y;Wang SZ;Zhong W;Liu BH;Tao HW
通讯作者:
Tao HW
影响因子:
8.2
作者:
Wu, Guangying K.;Tao, Huizhong W.;Zhang, Li I.
通讯作者:
Zhang, Li I.
影响因子:
3.4
作者:
Lin, John Y.;Lin, Michael Z.;Tsien, Roger Y.
通讯作者:
Tsien, Roger Y.
影响因子:
16.2
作者:
Miller, LM;Escabí, MA;Schreiner, CE
通讯作者:
Schreiner, CE