Dietary intake and risk of rheumatoid arthritis-a cross section multicenter study.
Dietary intake and risk of rheumatoid arthritis-a cross section multicenter study.
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膳食摄入量与类风湿性关节炎的风险——一项横断面多中心研究
DOI：
10.1007/s10067-016-3383-x
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发表时间：
2016-12
影响因子：
3.4
通讯作者：
Li, Zhan-Guo
中科院分区：
文献类型：
--
作者：
He, Jing;Wang, Yu;Feng, Min;Zhang, Xia;Jin, Yue-Bo;Li, Xue;Su, Lin-Chong;Liu, Shuang;Wang, Ai-Xue;Chen, Xiao-Mei;Wu, Li-Jun;Yu, Xiao-Xia;Xu, Ning;Liu, Xiang-Yuan;Yan, Hui-Ming;Wang, Yong-Fu;Jia, Bin;Li, Jun-Fang;Tao, Jie-Mei;Zhang, Feng-Xiao;Yu, Ping;Cui, Liu-Fu;Yang, Jing;Li, Zhen-Bin;Xie, Jian-Li;Wei, Ping;Sun, Wen-Wen;Gong, Lu;Cheng, Yong-Jing;Huang, Ci-Bo;Wang, Xiao-Yuan;Wang, Yi;Guo, Hui-Fang;Jin, Hong-Tao;Liu, Xia;Wang, Guo-Chun;Wang, Yan-Hua;He, Lan;Zhao, Yi;Li, Xiao-Xia;Zhang, Yan;Guo, Jian-Ping;Li, Zhan-Guo
环境因素在类风湿关节炎（RA）的发生发展中起重要作用。在这些因素中，吸烟通常被认为是RA的既定危险因素。关于饮食对RA发生风险影响的数据有限。本研究评估了饮食模式对中国人群RA易感性的影响。这是一项大规模的病例对照研究，包括968例RA患者和1037例匹配的健康对照。研究对象来自18所教学医院。社会人口学特征和饮食摄入量5年前的类风湿关节炎发作的自我问卷调查报告。病例组和对照组之间的消耗量差异用Student t检验进行分析。应用多元Logistic回归分析确定与RA易感性相关的独立饮食危险因素。与健康人相比，RA患者减少了蘑菇（P= 0.000），豆类（P= 0.006），柑橘（P= 0.000），家禽（P= 0.000），鱼（P = 0.000），可食用内脏（P= 0.018）和乳制品（P= 0.005）的消费。多变量分析显示，一些饮食项目可能对RA的发展有保护作用，如蘑菇（aOR = 0.669，95%CI = 0.518- 0.864，P = 0.002），柑橘类水果（aOR = 0.990，95%CI = 0.981- 0.999，P = 0.04），乳制品（aOR = 0.921，95%CI 0.867- 0.977，P = 0.006）。几种饮食因素对RA易感性有独立影响。饮食干预可以降低RA的风险。
Environmental factors play an important role in the development of rheumatoid arthritis (RA). Among these factors, smoking is generally considered to be an established risk factor for RA. Data regarding the impact of diet on risk of RA development is limited. This study assessed the impact of dietary patterns on RA susceptibility in Chinese populations. This was a large scale, case-control study composed of 968 patients with RA and 1037 matched healthy controls. Subjects were recruited from 18 teaching hospitals. Socio-demographic characteristics and dietary intakes 5 years prior to the onset of RA were reported by a self-administered questionnaire. Differences in quantity of consumption between cases and controls were analyzed by Student’sttest. Multiple logistic regression analysis was applied to identify independent dietary risk factor(s) responsible for RA susceptibility. Compared to healthy individuals, RA patients had decreased consumption of mushrooms (P= 0.000), beans (P= 0.006), citrus (P= 0.000), poultry (P= 0.000), fish (P= 0.000), edible viscera (P= 0.018), and dairy products (P= 0.005). Multivariate analyses revealed that several dietary items may have protective effects on RA development, such as mushrooms (aOR = 0.669; 95%CI = 0.518–0.864,P= 0.002), citrus fruits (aOR = 0.990; 95%CI = 0.981–0.999,P= 0.04), and dairy products (aOR = 0.921; 95%CI 0.867–0.977,P= 0.006). Several dietary factors had independent effects on RA susceptibility. Dietary interventions may reduce the risk of RA.
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影响因子：
4.9
作者：
Benito-Garcia E;Feskanich D;Hu FB;Mandl LA;Karlson EW
通讯作者：
Karlson EW
影响因子：
27.4
作者：
Sköldstam, L;Hagfors, L;Johansson, G
通讯作者：
Johansson, G
DOI：
10.7547/87507315-80-8-414
发表时间：
1990-08-01
影响因子：
0.7
作者：
DAVIS, RH;ROSENTHAL, KY;ROUW, GR
通讯作者：
ROUW, GR
影响因子：
4.9
作者：
Di Giuseppe D;Discacciati A;Orsini N;Wolk A
通讯作者：
Wolk A
影响因子：
5.1
作者：
Salminen, E;Heikkilä, S;Salminen, S
通讯作者：
Salminen, S