Dietary aspects related to health and obesity in Williams syndrome, Down syndrome, and Prader-Willi syndrome.
Dietary aspects related to health and obesity in Williams syndrome, Down syndrome, and Prader-Willi syndrome.
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DOI：
10.3402/fnr.v59.25487
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发表时间：
2015
影响因子：
3.3
通讯作者：
Kolset SO
中科院分区：
文献类型：
--
作者：
Nordstrøm M;Paus B;Andersen LF;Kolset SO
可能导致肥胖和继发性疾病的饮食方面在与智力残疾相关的遗传亚群中没有很好的记录。描述Prader-Willi综合征(PWS)、唐氏综合征(DS)和威廉姆斯综合征(WS)受试者的食物摄入频率，并探讨其与体重指数(BMI)的关系。探讨不同生活方式下DS患者与食物相关的自主性和摄入频率。调查了16~42岁WS(n=21)、DS(n=40)和PWS(n=20)人群的自报摄入量、血浆类胡萝卜素和红细胞中omega-3脂肪酸(FAs)含量。与患有DS和WS的参与者相比，患有PWS的参与者显示出更高比例的水果(p=0.012)和蔬菜(p=0.004)的摄入量，以及更高的血浆胡萝卜素(p<；0.001)。此外，与PWS和DS的参与者相比，WS的参与者中有更大比例的人是鱼类的低频率消费者(p=0.005)，不太可能使用omega-3脂肪酸补充剂(p=0.023)，并且降低了红细胞中长链omega-3 FA的浓度(p<；0.001)。DS组BMI与血浆类胡萝卜素呈负相关。与与亲戚住在一起的同龄人相比，居住在社区的参与者比例增加，表明他们高频率地摄入预煮好的食物(p=0.030)，并倾向于高频率地消费软饮料(p=0.079)。社区居民的参与者也更有可能经常参与与食物有关的决策和准备工作。与PWS患者相比，WS患者的饮食模式较差。居住在社区的人中有较大比例的人经常食用预先煮好的食物，并表现出高频率软饮料消费的趋势。此外，他们对被调查食物的摄取频率与与亲戚同住的人相似，但他们更频繁地参与食物的决策和准备。
Dietary aspects that might contribute to development of obesity and secondary conditions are not well documented in genetic subgroups associated with intellectual disability. To describe the intake frequencies of selected foods in participants with Prader–Willi syndrome (PWS), Down syndrome (DS), and Williams syndrome (WS), and investigate the association with body mass index (BMI). To explore food-related autonomy and intake frequencies among persons with DS in different living arrangements. Self-reported intake frequencies and measurement of plasma carotenoids and erythrocyte content of omega-3 fatty acids (FAs) were investigated in persons aged 16–42 years, with WS (n=21), DS (n=40), and PWS (n=20). A larger proportion of participants with PWS showed high-frequency intake of fruits (p=0.012) and vegetables (p=0.004), and had higher plasma carotenoids (p<0.001) compared to participants with DS and WS. Furthermore, a larger proportion of participants with WS were low-frequency consumers of fish (p=0.005), less likely to use omega-3 FA supplements (p=0.023), and had reduced erythrocyte concentrations of long-chain omega-3 FAs (p<0.001), compared to participants with PWS and DS. In DS, BMI was negatively associated with plasma carotenoids. Increased proportions of participants living in communities showed high-frequency intake of precooked meals (p=0.030), and a tendency toward high-frequency consumption of soft drinks (p=0.079), when compared to peers living with relatives. Participants in community residences were also more likely to participate frequently in food-related decisions and preparations. Persons with WS had a less-favorable dietary pattern when compared to persons with PWS. A larger proportion of persons living in communities frequently consumed precooked meals and showed a tendency of high-frequency soft drink consumption. Otherwise, their intake frequencies of the investigated foods were similar to those living with relatives, but they participated more frequently in decisions and preparations of foods.
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影响因子：
4.2
作者：
Eumann Mesas, Arthur;Guallar-Castillon, Pilar;Rodriguez-Artalejo, Fernando
通讯作者：
Rodriguez-Artalejo, Fernando
影响因子：
3.2
作者：
Al-Delaimy, WK;van Kappel, AL;Riboli, E
通讯作者：
Riboli, E
影响因子：
4.7
作者：
Brevik, A;Andersen, LF;Drevon, CA
通讯作者：
Drevon, CA
影响因子：
3.6
作者：
Carlsen, Monica H.;Karlsen, Anette;Andersen, Lene F.
通讯作者：
Andersen, Lene F.
影响因子：
64.8
作者：
Hattori, M;Fujiyama, A;Groner, Y
通讯作者：
Groner, Y