Impact of scanner hardware and imaging protocol on image quality and compartment volume precision in the ADNI cohort.
Impact of scanner hardware and imaging protocol on image quality and compartment volume precision in the ADNI cohort.
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DOI：
10.1016/j.neuroimage.2009.11.006
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发表时间：
2010-02-01
期刊：
影响因子：
5.7
通讯作者：
Muftuler, L. Tugan
中科院分区：
文献类型：
--
作者：
Kruggel, Frithjof;Turner, Jessica;Muftuler, L. Tugan
基于磁共振成像(MRI)数据的脑结构形态测量已成为神经生物学中的重要工具。最近对神经退行性疾病的多中心研究提出了体积测量的精度问题，以及它们对扫描仪特性和成像方案的依赖。本文分析了一个由843名受试者的1073次MRI检查组成的大型数据集，这些检查是在58个地点的90台扫描仪上获得的。使用一套全面的图像质量和内容测量来描述扫描仪硬件和成像协议对形态测量测量的可变性的影响。配备阵列线圈的扫描仪在图像质量测量方面比传统线圈显示出显著的优势。在类似系统中，1.5T的信号和对比度噪声比等于或略好于3.0T，而在高场系统中，白色/灰质组织的对比度通常更好。41名受试者在同一扫描仪上进行了重复的MRI检查，172名受试者在不同的扫描仪上进行了重复检查。在相同条件下重复容量测量的重测可靠性被发现足以跟踪个别受试者纵向检查的变化。然而，在同一受试者中使用不同的采集条件，体积测量的方差高达10倍。解释这一发现的两个可能因素是扫描仪依赖的几何误差和白质/灰质组织对比度的差异。
Morphometry of brain structures based on magnetic resonance imaging (MRI) data has become an important tool in neurobiology. Recent multicenter studies in neurodegenerative diseases raised the issue of the precision of volumetric measures, and their dependence on the scanner properties and imaging protocol. A large dataset consisting of 1073 MRI examinations in 843 subjects, acquired on 90 scanners at 58 sites, is analyzed here. A comprehensive set of image quality and content measures is used to describe the influence of the scanner hardware and imaging protocol on the variability of morphometric measures. Scanners equipped with array coils show a remarkable advantage over conventional coils in terms of image quality measures. The signal- and contrast-to-noise ratio in similar systems is equal or slightly better at 1.5 T than 3.0 T, while the white/grey matter tissue contrast is generally better on high-field systems. Repeated MRI investigations on the same scanner were available in 41 subjects, on different scanners in 172 subjects. The retest reliability of repeated volumetric measures under the same conditions was found as sufficient to track changes in longitudinal examinations in individual subjects. Using different acquisition conditions in the same subject, however, the variance of volumetric measures was up to 10 times greater. Two likely factors explaining this finding are scanner-dependent geometrical inaccuracies and differences in the white/grey matter tissue contrast.
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影响因子：
5.7
作者：
Jovicich J;Czanner S;Han X;Salat D;van der Kouwe A;Quinn B;Pacheco J;Albert M;Killiany R;Blacker D;Maguire P;Rosas D;Makris N;Gollub R;Dale A;Dickerson BC;Fischl B
通讯作者：
Fischl B
影响因子：
5.7
作者：
Shuter, Borys;Yeh, Ing Berne;Wang, Shih-Chang
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Wang, Shih-Chang
影响因子：
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Leow AD;Yanovsky I;Parikshak N;Hua X;Lee S;Toga AW;Jack CR Jr;Bernstein MA;Britson PJ;Gunter JL;Ward CP;Borowski B;Shaw LM;Trojanowski JQ;Fleisher AS;Harvey D;Kornak J;Schuff N;Alexander GE;Weiner MW;Thompson PM;Alzheimer's Disease Neuroimaging Initiative
通讯作者：
Alzheimer's Disease Neuroimaging Initiative
影响因子：
5.7
作者：
Hua X;Leow AD;Parikshak N;Lee S;Chiang MC;Toga AW;Jack CR Jr;Weiner MW;Thompson PM;Alzheimer's Disease Neuroimaging Initiative
通讯作者：
Alzheimer's Disease Neuroimaging Initiative
影响因子：
5.7
作者：
Jovicich, J;Czanner, S;Dale, A
通讯作者：
Dale, A