Differences between men and women in the clinical presentation of patients diagnosed with obstructive sleep apnea syndrome.
Differences between men and women in the clinical presentation of patients diagnosed with obstructive sleep apnea syndrome.
复制标题
诊断为阻塞性睡眠呼吸暂停综合征的患者临床表现的男性和女性差异。
作者：
Marha R Shepertycky;K. Banno;M. Kryger
研究目标
STUDY OBJECTIVES
Obstructive sleep apnea syndrome (OSAS) results from recurrent episodes of breathing cessation during sleep. Epidemiologic studies have shown that OSAS is more prevalent in men than women (4% vs 2%). Previous studies have explored gender-related differences in upper airway anatomy and function, hormone physiology, and polysomnographic findings. The aim of this study is to assess differences in clinical presentation between women and men with OSAS.
DESIGN
Retrospective chart review analysis.
SETTING
Tertiary university-based medical center
PARTICIPANTS
130 randomly selected women with OSAS matched individually with 130 men with OSAS for age, body mass index, apnea-hypopnea index, and Epworth Sleepiness Scale score.
INTERVENTIONS
N/A.
MEASUREMENTS AND RESULTS
Data were obtained from questionnaires and in-laboratory polysomnographic studies. There were no differences between the genders for age (48.0 +/- 1.1 years [mean +/- SEM] for women vs 47.6 +/- 1.0 years for men), body mass index (40.4 +/- 0.7 kg/m2 for women vs 40.0 +/- 0.6 kg/m2 for men), apnea-hypopnea index (36.8 +/- 3.3/hour for women vs 36.0 +/- 3.0/hour for men), or Epworth Sleepiness Scale score (12.45 +/- 0.53 for women vs 12.84 +/- 0.47 for men). Although snoring and sleepiness were similarly common in women and men, women more often described their main presenting symptoms as insomnia (odds ratio: 4.20; 95% confidence interval: 1.54-14.26) and were much more likely to have a history of depression (odds ratio: 4.60; 95% confidence interval: 1.71-15.49) and hypothyroid disease (odds ratio: 5.60; 95% confidence interval: 2.14-18.57). Women presented less often with a primary complaint of witnessed apnea (odds ratio: 0.66; 95% confidence interval: 0.38-1.12), consumed less caffeine per day (3.3 cups in women vs 5.2 cups in men; P = .0001), and admitted to less alcohol consumption (odds ratio: 0.36; 95% confidence interval: 0.18-0.70).
CONCLUSIONS
At the time of OSAS diagnosis, women with OSAS are more likely to be treated for depression, to have insomnia, and to have hypothyroidism than are men with the same degree of OSAS.
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影响因子：
158.5
作者：
YOUNG, T;PALTA, M;BADR, S
通讯作者：
BADR, S
影响因子：
--
作者：
T. Young;R. Hutton;L. Finn;S. Badr;M. Palta
通讯作者：
T. Young;R. Hutton;L. Finn;S. Badr;M. Palta
影响因子：
5
作者：
Newman, AB;Nieto, FJ;Quan, SF
通讯作者：
Quan, SF
DOI：
10.1210/jcem.86.3.7316
发表时间：
2001-03
期刊：
The Journal of clinical endocrinology and metabolism
影响因子：
--
作者：
Robert B. Fogel;A. Malhotra;G. Pillar;Stephen D. Pittman;A. Dunaif;D. White
通讯作者：
Robert B. Fogel;A. Malhotra;G. Pillar;Stephen D. Pittman;A. Dunaif;D. White
影响因子：
158.5
作者：
Peppard, PE;Young, T;Skatrud, J
通讯作者：
Skatrud, J