Review on Bovine Tuberculosis: An Emerging Disease Associated with Multidrug-Resistant Mycobacterium Species.
Review on Bovine Tuberculosis: An Emerging Disease Associated with Multidrug-Resistant Mycobacterium Species.
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DOI：
10.3390/pathogens11070715
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发表时间：
2022-06-21
期刊：
影响因子：
--
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中科院分区：
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牛结核病是一种严重的传染病，影响着广泛的驯养和野生动物，是世界范围内的经济和公共卫生负担。这种疾病是由牛分枝杆菌引起的，很少由其他致病分枝杆菌引起。当感染与多种药物和广泛耐药的牛分枝杆菌有关时，牛结核病的问题就变得复杂起来。牛结核病的早期诊断有许多技术，无论是死前还是死后，每一种技术都有其诊断的优点和局限性。死前技术依赖于细胞或体液免疫反应，而死后诊断依赖于足够的肉眼检查、触诊和随后的诊断程序，如细菌分离、特有的组织病理学和聚合酶链式反应(PCR)，以得出最终诊断。最近，测序和生物信息学工具在牛结核病的诊断中变得越来越重要，包括但不限于分型、突变检测、系统发育分析、分子流行病学和致病分支杆菌内发生的相互作用。因此，目前的综述包括对牛结核病作为一种疾病的考虑，传统和最近的诊断方法，以及耐多药分支杆菌物种的出现。
Bovine tuberculosis is a serious infectious disease affecting a wide range of domesticated and wild animals, representing a worldwide economic and public health burden. The disease is caused by Mycobacterium bovis and infrequently by other pathogenic mycobacteria. The problem of bovine tuberculosis is complicated when the infection is associated with multidrug and extensively drug resistant M. bovis. Many techniques are used for early diagnosis of bovine tuberculosis, either being antemortem or postmortem, each with its diagnostic merits as well as limitations. Antemortem techniques depend either on cellular or on humoral immune responses, while postmortem diagnosis depends on adequate visual inspection, palpation, and subsequent diagnostic procedures such as bacterial isolation, characteristic histopathology, and PCR to reach the final diagnosis. Recently, sequencing and bioinformatics tools have gained increasing importance for the diagnosis of bovine tuberculosis, including, but not limited to typing, detection of mutations, phylogenetic analysis, molecular epidemiology, and interactions occurring within the causative mycobacteria. Consequently, the current review includes consideration of bovine tuberculosis as a disease, conventional and recent diagnostic methods, and the emergence of MDR-Mycobacterium species.
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DOI：
10.3390/ani10091473
发表时间：
2020-08-21
期刊：
Animals : an open access journal from MDPI
影响因子：
--
作者：
Abbate JM;Arfuso F;Iaria C;Arestia G;Lanteri G
通讯作者：
Lanteri G
影响因子：
2.4
作者：
Bezos, Javier;Casal, Carmen;Dominguez, Lucas
通讯作者：
Dominguez, Lucas
影响因子：
3.8
作者：
Alvarez, A. H.;Gutierrez-Ortega, A.;Hinojoza-Loza, E.
通讯作者：
Hinojoza-Loza, E.
影响因子：
3.7
作者：
Ameni, Gobena;Tadesse, Konjit;Berg, Stefan
通讯作者：
Berg, Stefan
影响因子：
3.2
作者：
Anne, N. Sweetline;Ronald, B. S. M.;Thangavelu, A.
通讯作者：
Thangavelu, A.