Effects of photoperiod and experience on aggressive behavior in female California mice.
Effects of photoperiod and experience on aggressive behavior in female California mice.
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DOI：
10.1016/j.bbr.2009.12.038
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发表时间：
2010-04-02
影响因子：
2.7
通讯作者：
Trainor, Brian C.
中科院分区：
文献类型：
--
作者：
Silva, Andrea L.;Fry, William H. D.;Sweeney, Colleen;Trainor, Brian C.
在许多物种中都观察到雌性之间的攻击行为，但这种行为的机制在历史上一直没有得到充分的研究。在许多啮齿类动物中，与夏季一样的长日照相比，冬季一样的短日照诱导了更高的攻击水平。最近关于仓鼠的报告表明，短日照也会增加雌性仓鼠的攻击性。本研究探讨了光周期对雌性加州小鼠攻击行为的影响，并首次比较了不同光周期下攻击行为测试的雌性啮齿动物的脑活动。我们观察到雌性加州小鼠在短日照条件下比长日照条件下更具攻击性。有趣的是，我们还观察到，在长时间的女性攻击潜伏期下降，重复测试居民入侵者测试。这些数据表明，在男性中描述的赢家效应也可能发生在女性中。我们还使用磷酸化细胞外信号调节激酶（pERK）在大脑中的表达来估计攻击测试期间的大脑活动。pERK可以在短期内改变神经元活性，并且在长期内可以充当转录因子。使用免疫印迹分析，我们观察到，侵略诱导的pERK表达的女性床核的纹终末（BNST）和内侧杏仁核发生在长和短的日子。因此，控制短日照下攻击性增加的机制仍不清楚，需要进一步研究。
Aggressive behavior among females is observed in many species, but the mechanisms of this behavior have historically been understudied. In many species of rodents, winter-like short day photoperiods induce increased aggression levels compared to summer-like long day photoperiods. Recent reports in hamsters show that short days also increase aggression in females. We examined the effects of photoperiod on aggression in female California mice, and for the first time compare brain activity of aggression-tested female rodents under different photoperiods. We observed that female California mice were more aggressive when housed in short days versus long days. Intriguingly, we also observed that under long days female attack latency decreases with repeated testing in resident intruder tests. These data suggest that winner effects that have been described in males may also occur in females. We also used the expression of phosphorylated extracellular signal-regulated kinases (pERK) in the brain to estimate brain activity during aggression tests. pERK can alter neuronal activity in the short term and in the long term can act as a transcription factor. Using immunoblot analyses we observed that aggression-induced pERK expression in the female bed nucleus of the stria terminalis (BNST) and medial amygdala occurs under both long and short days. Thus, the mechanisms controlling increased aggression under short days are still unclear and additional study is needed.
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影响因子：
3.5
作者：
Davis, ES;Marler, CA
通讯作者：
Marler, CA
影响因子：
2.7
作者：
De Vries, GJ;Boyle, PA
通讯作者：
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DOI：
10.1098/rspb.2007.1707
发表时间：
2008-05-07
影响因子：
4.7
作者：
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通讯作者：
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作者：
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通讯作者：
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影响因子：
2.5
作者：
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通讯作者：
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