Dental x-rays and risk of meningioma.
Dental x-rays and risk of meningioma.
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DOI：
10.1002/cncr.26625
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发表时间：
2012-09-15
期刊：
影响因子：
6.2
通讯作者：
Wrensch M
中科院分区：
文献类型：
--
作者：
Claus EB;Calvocoressi L;Bondy ML;Schildkraut JM;Wiemels JL;Wrensch M
电离辐射是脑膜瘤的一个一贯被发现的潜在可改变的危险因素，脑膜瘤是美国报道最频繁的原发脑瘤。研究最常见的人工电离辐射源--牙科X光与颅内脑膜瘤风险之间的关系。基于人群的病例对照研究设计。这项研究包括2006年5月1日至2011年4月28日期间康涅狄格州、马萨诸塞州、北卡罗来纳州、旧金山湾区和德克萨斯州休斯敦8个县的居民确诊的1433例29-79岁的颅内脑膜瘤病例，以及在年龄、性别和地理位置上频率匹配的1350名对照。咬合、全口和牙科x光检查自我报告与颅内脑膜瘤诊断的关系。在一生中，病例报告曾经进行过咬合检查的可能性是对照组的两倍以上(优势比(OR)=2.0，95%可信区间(CI)1.4-2.9)。无论是在哪个年龄，报告每年或更频繁地收看咬人电影的人，在10岁、10-19岁、20-49岁和50岁以上的年龄段，其风险比分别为1.4(95%CI：1.0-1.8)、1.6(95%CI：1.2-2.0)、1.9(95%CI：1.4-2.6)和1.5(95%CI：1.1-2.0)。脑膜瘤风险的增加也与年轻时或每年或更频繁地拍摄Panorex电影有关，报告10岁以下接受此类电影的人患脑膜瘤的风险增加4.9倍(95%CI：1.8-13.2)。未发现肿瘤位于天幕上方或下方。暴露于过去的一些牙科X光，当时辐射暴露比现在的时代更大，似乎与颅内脑膜瘤的风险增加有关。与人工电离辐射的所有来源一样，考虑使用这种可改变的危险因素可能对患者有利。
Ionizing radiation is a consistently identified and potentially modifiable risk factor for meningioma, the most frequently reported primary brain tumor in the United States. To examine the association between dental x-rays, the most common artificial source of ionizing radiation, and risk of intra-cranial meningioma. Population-based case-control study design. The study includes 1433 intra-cranial meningioma cases aged 29-79 years diagnosed among residents of the states of Connecticut, Massachusetts, North Carolina, the San Francisco Bay Area and eight Houston, Texas counties between May 1, 2006 and April 28, 2011 and 1350 controls that were frequency-matched on age, sex and geography. The association of intra-cranial meningioma diagnosis with self-report of bitewing, full-mouth, and panorex dental x-rays. Over a lifetime, cases were more than twice (Odds ratio (OR) = 2.0, 95% confidence interval (CI), 1.4-2.9) as likely as controls to report having ever had a bitewing exam. Regardless of the age at which the films were received, persons who reported receiving bitewing films on a yearly or greater frequency had an elevated risk with odds ratios of 1.4 (95%CI: 1.0-1.8), 1.6 (95%CI: 1.2-2.0), 1.9 (95%CI: 1.4-2.6), and 1.5 (95%CI: 1.1-2.0) for ages <10, 10-19, 20-49, and 50+ years, respectively. Increased risk of meningioma was also associated with panorex films taken at a young age or on a yearly or greater frequency with persons reporting receiving such films under the age of 10 years at 4.9 times (95%CI: 1.8-13.2) increased risk of meningioma. No association was appreciated with location of tumor above or below the tentorium. Exposure to some dental x-rays performed in the past, when radiation exposure was greater than in the current era, appears to be associated with increased risk of intra-cranial meningioma. As with all sources of artificial ionizing radiation, considered use of this modifiable risk factor may be of benefit to patients.
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DOI：
10.1056/nejmoa0901249
发表时间：
2009-08-27
期刊：
The New England journal of medicine
影响因子：
--
作者：
Fazel R;Krumholz HM;Wang Y;Ross JS;Chen J;Ting HH;Shah ND;Nasir K;Einstein AJ;Nallamothu BK
通讯作者：
Nallamothu BK
影响因子：
15.9
作者：
Rajaraman, Preetha;Hutchinson, Amy;Inskip, Peter D.
通讯作者：
Inskip, Peter D.
影响因子：
158.5
作者：
RON, E;MODAN, B;KATZ, L
通讯作者：
KATZ, L
影响因子：
4.1
作者：
Umansky, Felix;Shoshan, Yigal;Spektor, Sergey
通讯作者：
Spektor, Sergey
影响因子：
4.8
作者：
Rodvall, Y;Ahlbom, A;Sp채nnare, B
通讯作者：
Sp채nnare, B