Cluster of SARS among medical students exposed to single patient, Hong Kong.
Cluster of SARS among medical students exposed to single patient, Hong Kong.
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DOI：
10.3201/eid1002.030452
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发表时间：
2004-02
影响因子：
11.8
通讯作者：
Outbreak Study Group
中科院分区：
文献类型：
--
作者：
Wong TW;Lee CK;Tam W;Lau JT;Yu TS;Lui SF;Chan PK;Li Y;Bresee JS;Sung JJ;Parashar UD;Outbreak Study Group
我们研究了严重急性呼吸系统综合症(SARS)在香港威尔斯亲王医院的首例SARS患者在其病情被确认之前，在医科学生中的传播模式。我们对66名参观了指标患者病房的医学生进行了回顾性队列研究，其中包括16名患有SARS的学生和50名健康学生。明确去过指示病例隔间的学生感染SARS的风险是没有去过的学生的七倍(10/27[41%]比1/20[5%]，相对风险[RR]7.4；95%可信区间[CI]1.0至53.3)。随着暴露于指示病例的接近，发病率直接增加。然而，8名学生中有4人感染了SARS，他们住在同一个隔间里，但不在指示病例患者的1米以内。接近指标病例-患者与传播有关，这与飞沫传播一致。不能排除通过病毒或小气雾剂传播的可能性。
We studied transmission patterns of severe acute respiratory syndrome (SARS) among medical students exposed exclusively to the first SARS patient in the Prince of Wales Hospital in Hong Kong, before his illness was recognized. We conducted a retrospective cohort study of 66 medical students who visited the index patient’s ward, including 16 students with SARS and 50 healthy students. The risk of contracting SARS was sevenfold greater among students who definitely visited the index case’s cubicle than in those who did not (10/27 [41%] versus 1/20 [5%], relative risk [RR] 7.4; 95% confidence interval [CI] 1.0 to 53.3). Illness rates increased directly with proximity of exposure to the index case. However, four of eight students who were in the same cubicle, but were not within 1 m of the index case-patient, contracted SARS. Proximity to the index case-patient was associated with transmission, which is consistent with droplet spread. Transmission through fomites or small aerosols cannot be ruled out.
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DOI：
10.1016/s0140-6736(03)13077-2
发表时间：
2003-04-19
期刊：
Lancet (London, England)
影响因子：
--
作者：
Peiris JS;Lai ST;Poon LL;Guan Y;Yam LY;Lim W;Nicholls J;Yee WK;Yan WW;Cheung MT;Cheng VC;Chan KH;Tsang DN;Yung RW;Ng TK;Yuen KY;SARS study group
通讯作者：
SARS study group
DOI：
10.1016/0035-9203(72)90271-4
发表时间：
1972-01-01
影响因子：
2.2
作者：
CAREY, DE;CASALS, J;KEMP, GE
通讯作者：
KEMP, GE
影响因子：
56.9
作者：
Lipsitch, M;Cohen, T;Murray, M
通讯作者：
Murray, M
DOI：
10.1016/s0140-6736(03)13168-6
发表时间：
2003-05-03
期刊：
Lancet (London, England)
影响因子：
--
作者：
Seto WH;Tsang D;Yung RW;Ching TY;Ng TK;Ho M;Ho LM;Peiris JS;Advisors of Expert SARS group of Hospital Authority
通讯作者：
Advisors of Expert SARS group of Hospital Authority
影响因子：
6.4
作者：
Khan, AS;Tshioko, FK;Ksiazek, TG
通讯作者：
Ksiazek, TG