The impact of anthelmintic drugs on weight gain of smallholder goats in subtropical regions.
The impact of anthelmintic drugs on weight gain of smallholder goats in subtropical regions.
复制标题
驱虫药对亚热带地区小山羊的体重增加的影响。
DOI：
10.1016/j.prevetmed.2018.08.014
复制
发表时间：
2018-11-01
影响因子：
2.6
通讯作者：
Wambura P
中科院分区：
文献类型：
--
作者：
Bessell PR;Sargison ND;Mirende K;Dash R;Prasad S;Al-Riyami L;Gammon N;Stuke K;Woolley R;Barbaruah M;Wambura P
驱虫药对印度和坦桑尼亚山羊体重影响的评估在56天内，印度接受驱虫药的山羊体重增加速度几乎是未接受驱虫药的山羊的两倍。在56天内，坦桑尼亚接受治疗的山羊比未接受治疗的山羊增加了15%的体重。在这两个地区，接受治疗的山羊的身体状况评分也比未接受治疗的山羊有所改善。蠕虫感染被认为是小农生产系统中山羊生产力的主要障碍。我们使用了一个多层次的框架，以估计当地可用的驱虫药管理的影响，可以对山羊的体重增加在印度和坦桑尼亚的小农设置。我们从印度奥里萨邦的92个家庭招募了234只山羊，从坦桑尼亚多多玛区的15个家庭招募了253只山羊。山羊是未怀孕的成年雌性，并且在可能的情况下从每个家庭至少招募两只山羊。将每只山羊随机分配至当地可用的驱虫药物治疗组或非治疗组。对每只动物进行标记、称重并评估其身体状况评分（BCS）。在28天和56天后对动物进行随访并重新称重。为了解释蠕虫暴露的当地差异以及家庭和畜群之间的差异，在多水平混合模型中分析了数据，其中村庄中的畜群作为嵌套随机效应。在56天的研究中，印度未接受治疗的山羊平均每天增加30.64 g（每日增加0.23%基线体重），坦桑尼亚为66.01 g（0.33%基线体重）。从混合模型来看，印度接受治疗的山羊平均每天比未接受治疗的山羊多增重25.22 g，这显著大于未接受治疗的山羊的增重（p < 0.001）。在坦桑尼亚，接受治疗的山羊比未接受治疗的山羊平均每天增加9.878 g，这也显著高于未接受治疗的山羊（p = 0.007）。此外，在印度和坦桑尼亚，在基线调查中体重较轻的山羊体重增加了更多。在这两项研究中，接受治疗的山羊的BCS比未接受治疗的山羊改善更大。在这项研究中，我们已经证明，在某些情况下，驱虫药物的管理有一个明确的有益影响山羊体重。
An assessment of the impacts of anthelminthic drugs on weights of goats in India and Tanzania Over 56 days, the treated goats in India gained weight at almost twice the rate of non-treated goats. Over 56 days the treated goats in Tanzania gained 15% more weight than non-treated goats In both areas, the body condition scores of treated goats also improved relative to non-treated goats. Helminth infections are recognised as a major impediment to the productivity of goats in smallholder production systems. We used a multilevel framework to estimate the impact that administration of locally available anthelminthic drugs can have on the weight gains of goats in smallholder settings in India and Tanzania. We recruited 234 goats from 92 households from Odisha state in India and 253 goats from 15 households from Dodoma region in Tanzania. The goats were non-pregnant adult females, and from each household a minimum of two goats were recruited wherever possible. Each goat was randomly assigned to treatment with a locally available anthelminthic drug, or non-treatment. Each animal was tagged, weighed and had its body condition score (BCS) assessed. Animals were followed up after 28 and 56 days and re-weighed. To account for the local variations in exposure to helminths and for variations between households and herds, the data were analysed in a multilevel mixed model with herd in village as nested random effects. Over the 56 days of study, the non-treated goats in India had gained a mean of 30.64 g per day (a daily gain of 0.23% baseline body weight) and in Tanzania 66.01 g per day (0.33% baseline body weight). From the mixed model, the treated goats in India gained a mean of 25.22 g per day more than non-treated goats, this is significantly greater than the weight gain in non-treated goats (p < 0.001). In Tanzania treated goats gained a mean of 9.878 g per day more than non-treated goats, which is also significantly greater than non-treated goats (p = 0.007). Furthermore, in India and Tanzania, goats with a lighter weight at the baseline survey gained greater amounts of weight. In both studies the BCS of the treated goats improved by a greater amount than the non-treated goats. In this study we have demonstrated that in certain settings, the administration of anthelminthic drugs has a clear beneficial impact on goat weight.
登录
查看更多内容
影响因子：
1.7
作者：
Keyyu, J. D.;Kyvsgaard, N. C.;Kassuku, A. A.
通讯作者：
Kassuku, A. A.
DOI：
10.1007/s12639-016-0818-x
发表时间：
2017-06-01
期刊：
Journal of parasitic diseases : official organ of the Indian Society for Parasitology
影响因子：
--
作者：
Dixit, Alok Kumar;Das, Giridhari;Baghel, Ramesh Pratap Singh
通讯作者：
Baghel, Ramesh Pratap Singh
影响因子：
2
作者：
COOP, RL;SYKES, AR;ANGUS, KW
通讯作者：
ANGUS, KW
影响因子：
2.2
作者：
Keyyu, J. D.;Kassuku, A. A.;Monrad, J.
通讯作者：
Monrad, J.
影响因子：
2.2
作者：
Keyyu, JD;Kassuku, AA;Kyvsgaard, NC
通讯作者：
Kyvsgaard, NC