Brief report: approaches to 31P-MRS in awake, non-sedated children with and without autism spectrum disorder.
Brief report: approaches to 31P-MRS in awake, non-sedated children with and without autism spectrum disorder.
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DOI:
10.1007/s10803-011-1359-x
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发表时间:
2012-06
影响因子:
3.9
通讯作者:
Golomb, Beatrice A.
中科院分区:
文献类型:
--
作者:
Erickson, Laura C.;Scott-Van Zeeland, Ashley A.;Hamilton, Gavin;Lincoln, Alan;Golomb, Beatrice A.
We piloted a suite of approaches aimed to facilitate a successful series of up to four brain and muscle 31Phosphorus-Magnetic Resonance Spectroscopy (31P-MRS) scans performed in one session in 12 awake, non-sedated subjects (ages 6 – 18), 6 with autism spectrum disorders (ASD) and 6 controls. We targeted advanced preparation, parental input, physical comfort, short scan protocols, allocation of extra time, and subject emotional support. 100% of subjects completed at least one brain scan and one leg muscle scan: 42 of 46 attempted scans were completed (91%), with failures dominated by exercise muscle scans (completed in 6/6 controls but 3/6 cases). One completed scan lacked usable data unrelated to subject/scan procedure (orthodonture affected a frontal brain scan). As a group, these methods provide a foundation for conduct and enhancement of future MR studies in pediatric subjects with ASD.
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影响因子:
3.9
作者:
Cicchetti, Domenic V.;Lord, Catherine;Volkmar, Fred R.
通讯作者:
Volkmar, Fred R.
影响因子:
2.3
作者:
Ross, AK;Hazlett, HC;Piven, J
通讯作者:
Piven, J
影响因子:
3.6
作者:
Light, David;Arvanitis, Georgia M.;Glasberg, Scot B.
通讯作者:
Glasberg, Scot B.
DOI:
10.1097/00004583-199706000-00024
发表时间:
1997-06-01
影响因子:
13.3
作者:
Rosenberg, DR;Sweeney, JA;Thulborn, KR
通讯作者:
Thulborn, KR
影响因子:
9
作者:
PORIES, WJ;SWANSON, MS;DOHM, L
通讯作者:
DOHM, L