Incidence of specific absolute neurocognitive impairment in globally intact children with histories of early severe deprivation.
Incidence of specific absolute neurocognitive impairment in globally intact children with histories of early severe deprivation.
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DOI：
10.1080/09297040802244136
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发表时间：
2008-09
影响因子：
2.2
通讯作者：
Chugani, Harry T.
中科院分区：
文献类型：
--
作者：
Behen, Michael E.;Helder, Emily;Rothermel, Robert;Solomon, Katherine;Chugani, Harry T.
产后剥夺与神经认知延迟/功能障碍有关。虽然“追赶”的全球认知收养后，已报告，本研究探讨了特定的绝对损害的发病率在收养儿童完整的全球认知功能。对85名出生后在孤儿院长大的儿童（38名男性，平均年龄=112.8个月，标准差=30.3个月;范围61 - 209个月）进行了全面的神经心理学评估。其中54人被认为是整体完整的（IQ>85）。在那些被认为整体完好的人中，46%的人在至少一个功能领域表现出绝对障碍。在孤儿院停留的时间直接与损害的发生率和受影响的领域的数量。相当大比例的参与者在一个或多个神经认知功能领域表现出持续的、绝对的损害，尽管基本的智力功能是完整的。
Postnatal deprivation is associated with neurocognitive delay/dysfunction. Although “catch up” in global cognition following adoption has been reported, this study examined the incidence of specific absolute impairment in adopted children with intact global cognitive functioning. Eighty-five children (38 males, mean age=112.8, SD=30.3 months; range 61−209 months) raised from birth in orphanages underwent comprehensive neuropsychological evaluation. Fifty-four were deemed globally intact (IQ>85). Of those deemed globally intact, 46 percent evidenced absolute impairment in at least one domain of functioning. Duration of stay in the orphanage was directly associated with incidence of impairment and number of domains affected. A substantial proportion of participants evidenced persistent, absolute impairment in one or more domains of neurocognitive function despite integrity of basic intellectual functions.
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