Identification and isolation of insecticidal oxazoles from Pseudomonas spp.
Identification and isolation of insecticidal oxazoles from Pseudomonas spp.
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DOI：
10.3762/bjoc.8.85
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发表时间：
2012
影响因子：
2.7
通讯作者：
Bode HB
中科院分区：
文献类型：
--
作者：
Grundmann F;Dill V;Dowling A;Thanwisai A;Bode E;Chantratita N;Ffrench-Constant R;Bode HB
从两种不同的假单胞菌菌株中鉴定出两种新的和五种已知的恶唑，此外还鉴定出已知的吡喃酮类假吡喃酮A和B。标记实验证实了它们的结构，并为这些天然恶唑的新生物合成途径提供了初步证据。为了确认它们的结构，合成了它们，这也允许测试它们的生物活性。此外，还研究了合成中间体的生物活性，揭示了几种化合物的有趣的生物活性，尽管它们的总体结构简单。
Two new and five known oxazoles were identified from two different Pseudomonas strains in addition to the known pyrones pseudopyronine A and B. Labeling experiments confirmed their structures and gave initial evidence for a novel biosynthesis pathway of these natural oxazoles. In order to confirm their structure, they were synthesized, which also allowed tests of their bioactivity. Additionally, the bioactivities of the synthesis intermediates were also investigated revealing interesting biological activities for several compounds despite their overall simple structures.
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影响因子：
5.1
作者：
Pettit, GR;Knight, JC;Schmidt, JM
通讯作者：
Schmidt, JM
影响因子：
5.1
作者：
Kong, FM;Singh, MP;Carter, GT
通讯作者：
Carter, GT
影响因子：
10.7
作者：
SAITOU, N;NEI, M
通讯作者：
NEI, M
影响因子：
3.3
作者：
Chu, M;Mierzwa, R;Chan, TM
通讯作者：
Chan, TM
影响因子：
46.9
作者：
Vodovar, Nicolas;Vallenet, David;Boccard, Frédéric
通讯作者：
Boccard, Frédéric