Drug Combinations against Mucor irregularis In Vitro
Drug Combinations against Mucor irregularis In Vitro
复制标题
体外抗不规则毛霉的药物组合
DOI:
10.1128/aac.02612-12
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发表时间:
2013-04
影响因子:
4.9
通讯作者:
Yu, Jin
中科院分区:
文献类型:
--
作者:
Zhang, Shuzhen;Li, Ruoyu;Yu, Jin
ABSTRACT Combinations of terbinafine or caspofungin with amphotericin B, posaconazole, or itraconazole were studied as potential treatments against 18 isolates of Mucor irregularis in vitro. Synergism of the combinations of terbinafine with amphotericin B, posaconazole, and itraconazole against 38.9, 33.3, and 44.4% of the strains studied was observed. In contrast, synergism of the combinations of caspofungin with amphotericin B, posaconazole, and itraconazole against 99.4, 66.7, and 99.4% of the strains studied was observed. Furthermore, no antagonism was observed.
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