J-curve relation between daytime nap duration and type 2 diabetes or metabolic syndrome: A dose-response meta-analysis.
J-curve relation between daytime nap duration and type 2 diabetes or metabolic syndrome: A dose-response meta-analysis.
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DOI：
10.1038/srep38075
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发表时间：
2016-12-02
影响因子：
4.6
通讯作者：
Kadowaki T
中科院分区：
文献类型：
--
作者：
Yamada T;Shojima N;Yamauchi T;Kadowaki T
充足的睡眠对健康很重要，但由于社会因素，要做到这一点并不总是那么容易。白天小睡在世界各地普遍存在。我们进行了一项荟萃分析，以调查午睡(或白天过度嗜睡：EDS)与2型糖尿病或代谢综合征的风险之间的关系，并使用三次样条法模型量化潜在的剂量-反应关系。在电子数据库中搜索截至2016年发表的文章，涉及288,883个亚洲和西方主题。合并分析显示，长时间午睡(≥60 分钟/天)和EDS分别与不午睡或没有EDS相比，2型糖尿病的风险增加(优势比为1.46(95%CI 1.23~1.74，p <； 0.01)和2.00(1.58~2.53))。相比之下，短时间的午睡(60 /天)与糖尿病无关(p = 0.75)。剂量-反应荟萃分析显示，午睡时间与糖尿病或代谢综合征的风险之间呈J曲线关系，每天午睡约40 分钟没有任何影响，随后午睡时间较长，风险急剧增加。总而言之，午睡时间越长，患代谢性疾病的风险越高。还需要进一步的研究来证实短暂小睡的益处。
Adequate sleep is important for good health, but it is not always easy to achieve because of social factors. Daytime napping is widely prevalent around the world. We performed a meta-analysis to investigate the association between napping (or excessive daytime sleepiness: EDS) and the risk of type 2 diabetes or metabolic syndrome, and to quantify the potential dose-response relation using cubic spline models. Electronic databases were searched for articles published up to 2016, with 288,883 Asian and Western subjects. Pooled analysis revealed that a long nap (≥60 min/day) and EDS were each significantly associated with an increased risk of type 2 diabetes versus no nap or no EDS (odds ratio 1.46 (95% CI 1.23–1.74, p < 0.01) for a long nap and 2.00 (1.58–2.53) for EDS). In contrast, a short nap (<60 min/day) was not associated with diabetes (p = 0.75). Dose-response meta-analysis showed a J-curve relation between nap time and the risk of diabetes or metabolic syndrome, with no effect of napping up to about 40 minutes/day, followed by a sharp increase in risk at longer nap times. In summary, longer napping is associated with an increased risk of metabolic disease. Further studies are needed to confirm the benefit of a short nap.
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影响因子：
16.2
作者：
Cappuccio FP;D'Elia L;Strazzullo P;Miller MA
通讯作者：
Miller MA
影响因子：
4.7
作者：
Hayashi, M;Watanabe, M;Hori, T
通讯作者：
Hori, T
影响因子：
16.2
作者：
Ohkuma T;Fujii H;Iwase M;Kikuchi Y;Ogata S;Idewaki Y;Ide H;Doi Y;Hirakawa Y;Nakamura U;Kitazono T
通讯作者：
Kitazono T
影响因子：
4.4
作者：
Milner, Catherine E.;Cote, Kimberly A.
通讯作者：
Cote, Kimberly A.
影响因子：
5.6
作者：
Gillberg, M;Kecklund, G;Akerstedt, T
通讯作者：
Akerstedt, T