Retinopathy of prematurity: a review of risk factors and their clinical significance.
Retinopathy of prematurity: a review of risk factors and their clinical significance.
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DOI:
10.1016/j.survophthal.2018.04.002
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发表时间:
2018-09
影响因子:
5.1
通讯作者:
Chiang MF
中科院分区:
文献类型:
--
作者:
Kim SJ;Port AD;Swan R;Campbell JP;Chan RVP;Chiang MF
Retinopathy of prematurity (ROP) is a retinal vasoproliferative disease that affects premature infants. Despite improvements in neonatal care and management guidelines, ROP remains a leading cause of childhood blindness worldwide. Current screening guidelines are primarily based on two risk factors: birth weight and gestational age; however, many investigators have suggested other risk factors, including maternal factors, prenatal and perinatal factors, demographics, medical interventions, comorbidities of prematurity, nutrition, and genetic factors. We review the existing literature addressing various possible ROP risk factors. Although there have been contradictory reports, and the risk may vary between different populations, understanding ROP risk factors is essential to develop predictive models, to gain insights into pathophysiology of retinal vascular diseases and diseases of prematurity, and to determine future directions in management and research in ROP.
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DOI:
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Clinical ophthalmology (Auckland, N.Z.)
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