Arterial flow characteristics in the presence of vascular disease and implications for fast spin echo-based noncontrast MR angiography.
Arterial flow characteristics in the presence of vascular disease and implications for fast spin echo-based noncontrast MR angiography.
复制标题
DOI：
10.1002/jmri.22812
复制
发表时间：
2011-12
影响因子：
4.4
通讯作者：
Lee, Vivian S.
中科院分区：
文献类型：
--
作者：
Storey, Pippa;Lim, Ruth P.;Kim, Sooah;Stoffel, David R.;Lee, Vivian S.
研究血管疾病背景下的动脉血流特征，并检查其对基于快速自旋回波（FSE）的非对比MR血管造影（NC-MRA）性能的影响。17例患者是从预定在1.5T进行下肢常规对比增强MR血管造影（CE-MRA）的患者中招募的。检查的研究部分是在临床指示的方案之前进行的，包括腿部多个水平的相位对比成像和小腿和大腿的基于FSE的NC-MRA，使用3D ECG门控技术，该技术利用了舒张期和收缩期之间动脉流速的差异。血管闭塞与收缩期流速降低、收缩期峰值延迟以及两名中年患者的舒张期流速增加相关。在1例溃疡不愈合的受试者中观察到收缩期和舒张期流速升高。NC-MRA可以显示收缩期流速低至3 cm/s的动脉，舒张期流速高至6 cm/s时显示与CE-MRA相当的显示。在观察到的最高舒张期速度（15 cm/s）下，动脉描绘严重退化。目前实施的基于FSE的NC-MRA在宽范围的流动模式上成功地执行，但不适应极低的收缩期速度或非常高的舒张期速度。
To investigate arterial flow characteristics in the setting of vascular disease, and examine their effect on the performance of fast spin-echo (FSE)-based noncontrast MR angiography (NC-MRA). Seventeen patients were recruited from among those scheduled for routine contrast-enhanced MR angiography (CE-MRA) of the lower extremities at 1.5T. The research portion of the exam was performed prior to the clinically-indicated protocol and included phase-contrast imaging at multiple levels in the legs and FSE-based NC-MRA in the calf and thigh, using a 3D ECG-gated technique that exploits differences in arterial flow velocity between diastole and systole. Vascular occlusions were associated with reduced systolic velocity, a delayed systolic peak, and, in two middle-aged patients, an increase in diastolic velocity. Elevated systolic and diastolic velocities were observed in a subject with a non-healing ulcer. NC-MRA allowed visualization of arteries with systolic velocities as low as 3 cm/s, and exhibited comparable depiction to CE-MRA for diastolic velocities as high as 6 cm/s. At the highest diastolic velocities observed (15 cm/s) arterial depiction was severely degraded. FSE-based NC-MRA as presently implemented performs successfully over a wide range of flow patterns, but does not accommodate extremely low systolic velocities or very high diastolic velocities.
登录
查看更多内容
影响因子：
3.3
作者：
Busse, Reed F.;Brau, Anja C. S.;Vu, Anthony;Michelich, Charles R.;Bayram, Ersin;Kijowski, Richard;Reeder, Scott B.;Rowley, Howard A.
通讯作者：
Rowley, Howard A.
影响因子：
3.3
作者：
Edelman, Robert R.;Sheehan, John J.;Dunkle, Eugene;Schindler, Nancy;Carr, James;Koktzoglou, Ioannis
通讯作者：
Koktzoglou, Ioannis
影响因子：
3.3
作者：
Song, Ting;Laine, Andrew F.;Chen, Qun;Rusinek, Henry;Bokacheva, Louisa;Lim, Ruth P.;Laub, Gerhard;Kroeker, Randall;Lee, Vivian S.
通讯作者：
Lee, Vivian S.
影响因子：
19.7
作者：
Hodnett, Philip A.;Koktzoglou, Ioannis;Edelman, Robert R.
通讯作者：
Edelman, Robert R.
影响因子：
5
作者：
Hoey, Edward T. D.;Ganeshan, Arul;Crowe, Paul M.
通讯作者：
Crowe, Paul M.